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GSK-1838705A

GSK-1838705A

Product ID G7540
Cas No. 1116235-97-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $84.10 Please Inquire
5 mg $252.30 Please Inquire
25 mg $718.60 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

GSK-1838705A is an inhibitor of anaplastic lymphoma kinase (ALK) and IGF-1R that exhibits anticancer chemotherapeutic activity. This compound inhibits cell and tumor growth in a variety of cancers, including non-small cell lung cancer (NSCLC), neuroblastoma, and large-cell lymphoma.

Product Info

Cas No.

1116235-97-2

Purity

≥98%

Formula

C27H29FN8O3

Formula Wt.

532.57

Chemical Name

2-[[2-[[1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydroindol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methylbenzamide

IUPAC Name

2-[[2-[[1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydroindol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methylbenzamide

Synonym

GSK1838705A; GSK 1838705A; GSK1838705

Solubility

DMSO 107 mg/mL (200.91 mM) Water Insoluble Ethanol Insoluble

Appearance

Yellow to pale yellow powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G7540 MSDS PDF

Info Sheet

G7540 Info Sheet PDF

References

Sabbatini P, Korenchuk S, Rowand JL, et al. GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers. Mol Cancer Ther. 2009 Oct;8(10):2811-20. PMID: 19825801.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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