Histatin 5

Name: Histatin 5
SKU: H3273
Availability: InStock

Product ID H3273

Cas No. 115966-68-2

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Histatin 5 is an endogenous antimicrobial peptide (AMP) present in the salivary gland. Histatin 5 exhibits anti-inflammatory, antibacterial, and antifungal activities. In myeloid dendritic cells, histatin 5 binds Poryphyromonas hemagglutinin B, inhibiting production of MIP-1α, MIP-1β, and TNF-α. Histatin binds bacterial DNA, displaying bactericidal activity against gram positive bacteria such as Streptococcus. Additionally, histatin 5 causes ion flux-induced cell death of Candida cells in an ex vivo model of oral candidiasis.

Product Info

Cas No.	115966-68-2
Purity	≥95%
Formula	C₁₃₃H₁₉₅N₅₁O₃₃
Formula Wt.	3036.36
Solubility	Soluble in water.
Appearance	White to off white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	H3273 MSDS PDF
Info Sheet	H3273 Info Sheet PDF

References

Borgwardt DS, Martin AD, Van Hemert JR, et al. Histatin 5 binds to Porphyromonas gingivalis hemagglutinin B (HagB) and alters HagB-induced chemokine responses. Sci Rep. 2014 Jan 29;4:3904. PMID: 24473528.

Huo L, Zhang K, Ling J, et al. Antimicrobial and DNA-binding activities of the peptide fragments of human lactoferrin and histatin 5 against Streptococcus mutans. Arch Oral Biol. 2011 Sep;56(9):869-76. PMID: 21382611.

Peters BM, Zhu J, Fidel PL Jr, et al. Protection of the oral mucosa by salivary histatin-5 against Candida albicans in an ex vivo murine model of oral infection. FEMS Yeast Res. 2010 Aug 1;10(5):597-604. PMID: 20491938.

Jang WS, Bajwa JS, Sun JN, et al. Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans. Mol Microbiol. 2010 Jul;77(2):354-70. PMID: 20487276.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Histatin 5

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Granisetron Hydrochloride

AT-121

Ethacridine Lactate Monohydrate

SR-717 Lithium Salt

Cefotaxime Acid

Cyromazine

Indirubin

Esomeprazole Potassium

Acetyl-L-Carnitine Hydrochloride

Meropenem Sodium Carbonate

Erythromycin Thiocyanate

LY-364947

MK-0752

Copper Bis-3,5-diisopropylsalicylate

G250.A2 Peptide

Okadaic Acid Ammonium

Bis(3,5-dibromosalicyl) Fumarate

Glucagon-like Peptide I Amide (7-36), human

Tenovin-3

Naphazoline Hydrochloride

Footer