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HT-2 Toxin

HT-2 Toxin

Product ID T7676
Cas No. 26934-87-2
Purity ≥98%, TLC, HPLC
Product Unit SizeCostQuantityStock
0.5 mg $194.70 In stock
1 mg $369.10 In stock
5 mg $1,461.30 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

HT-2 toxin is a trichothecene mycotoxin initially produced by Fusarium and is also a metabolite of T2 toxin. HT-2 toxin is often produced in grains used as livestock feed and in the production of products for human consumption such as cereal. HT-2 toxin passes across the blood-brain barrier more easily than T2 toxin, exhibiting neurotoxicity by inducing apoptosis.

Product Info

Cas No.

26934-87-2

Purity

≥98%, TLC, HPLC

Formula

C22H32O8

Formula Wt.

424.48

Chemical Name

[(1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate

IUPAC Name

[(1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate

Synonym

NSC278571, Mycotoxin HT 2

Melting Point

151-152°C

Solubility

Soluble in Ethanol, DMSO. Very slightly soluble in water.

Appearance

Colorless Film

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

T7676 MSDS PDF

Info Sheet

T7676 Info Sheet PDF

References

Ortiz J, Van Camp J, Mestdagh F, et al. Mycotoxin co-occurrence in rice, oat flakes and wheat noodles used as staple foods in Ecuador. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013 Dec 7. [Epub ahead of print]. PMID: 24313870.

Weidner M, Hüwel S, Ebert F, et al. Influence of T-2 and HT-2 toxin on the blood-brain barrier in vitro: new experimental hints for neurotoxic effects. PLoS One. 2013;8(3):e60484. PMID: 23544145.

Zhang Y, Liu H, Lin X, et al. Dysregulation of cells cycle and apoptosis in human induced pluripotent stem cells chondrocytes through p53 pathway by HT-2 toxin: an in vitro study. Frontiers in Gen. 2021 Aug 4;12:677723. PMID: 34421989.

Custom Order

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