Description
Imazalil is a triazole fungicide used in veterinary medicine. Imazalil exhibits antifungal activity through inhibition of sterol 14-α demethylase, preventing ergosterol biosynthesis and cell wall formation. Imazalil also inhibits androgen receptors and aromatase through a mixed competitive/noncompetitive mode in vitro. This compound exhibits teratogenic effects on vertebrate development, affecting genes involved in retinoic acid signaling and altering neural differentiation in the nervous system.