LKT Labs

Biochemicals for Life Science Research

Incensol

Incensol

Product ID I524086
Cas No. 22419-74-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $120.20 Please Inquire
5 mg $338.00 Please Inquire
10 mg $601.00 Please Inquire
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Description

Incensol is a natural constituent found in frankincense resin and is a potent bioactive diterpenic cembrenoid. Frankincense extract has traditionally been used to treat various inflammatory diseases including arthritis. Several of the individual components in frankincense, including incensol, have shown anti-inflammatory activity in mice. Incensol was found to activate transient receptor potential vanilloid 3, a protein that is involved in temperature sensation in the skin, hair growth, and neurological activities. Incensol has also been found to inhibit activation of Burkitt’s lymphoma derived Raji cells.

Product Info

Cas No.

22419-74-5
Purity

≥98%
Formula

C20H34O2
Formula Wt.

306.49
Chemical Name

(1R,2S,5E,9E,12S)-1,5,9-Trimethyl-12-propan-2-yl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol
IUPAC Name

1,5,9-trimethyl-12-propan-2-yl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol
Synonym

Incensole, (-)-Incensol, (-)-Incensole
Solubility

Soluble in DMSO, dichloromethane or ethyl ether. Insoluble in water. Almost insoluble in ethanol or methanol.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

I524086 MSDS PDF
Info Sheet

I524086 Info Sheet PDF

References

Banno N, Akihisa T, Yasukawa K, et al. Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. J Ethnopharmacol. 2006 Sep 19;107(2):249-253. PMID: 16621377.

Pollastro F, Golin S, Chianese G, et al. Neuroactive and anti-inflammatory frankincense cembranes: a structure-activity study. J Nat Prod. 2016 Jul 22;79(7):1762-1768. PMID: 27352042.

Akihisa T, Tabata K, Banno N, et al. Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri. Biol Pharm Bull. 2006 Sep;29(9):1976-1979. PMID: 16945622.

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