• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dihydrochelerythrine

Dihydrochelerythrine

Product ID D3428
Cas No. 6880-91-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $63.60 In stock
5 mg $155.00 In stock
25 mg $583.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dihydrochelerythrine (DHC) is a benzophenanthridine alkaloid originally found in the stem bark of Garcinia. This compound exhibits a wide variety of antimicrobial activities (anti-parasitic, antifungal, and antibacterial) as well as anticancer, analgesic, and anti-inflammatory properties. DHC is active against Trypanosoma, Leishmania, Botrytis, Erysiphe, Candida, and various gram positive and gram negative bacteria. Additionally, DHC induces dissipation of the mitochondrial membrane potential in leukemia cells, resulting in apoptosis and necrosis. This compound also binds DNA sequences containing contiguous G or C base pairs.

Product Info

Cas No.

6880-91-7

Purity

≥98%

Formula

C21H19NO4

Formula Wt.

349.38

IUPAC Name

1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine

Solubility

10mM in DMSO 10mM in water

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

D3428 MSDS PDF

Info Sheet

D3428 Info Sheet PDF

References

Yao JY, Zhou ZM, Li XL, et al. Antiparasitic efficacy of dihydrosanguinarine and dihydrochelerythrine from Macleaya microcarpa against Ichthyophthirius multifiliis in richadsin (Squaliobarbus curriculus). Vet Parasitol. 2011 Dec 29;183(1-2):8-13. PMID: 21813242.

Feng G, Zhang J, Liu YQ. Inhibitory activity of dihydrosanguinarine and dihydrochelerythrine against phytopathogenic fungi. Nat Prod Res. 2011 Jul;25(11):1082-9. PMID: 21500094.

Vrba J, Dolezel P, Vicar J, et al. Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells. Toxicol In Vitro. 2008 Jun;22(4):1008-17. PMID: 18358694.

Fotie J, Bohle DS, Olivier M, et al. Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida. J Nat Prod. 2007 Oct;70(10):1650-3. PMID: 17880175.

Hu J, Zhang WD, Liu RH, et al. Benzophenanthridine alkaloids from Zanthoxylum nitidum (Roxb.) DC, and their analgesic and anti-inflammatory activities. Chem Biodivers. 2006 Sep;3(9):990-5. PMID: 17193331.

Bai LP, Zhao ZZ, Cai Z, et al. DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine. Bioorg Med Chem. 2006 Aug 15;14(16):5439-45. PMID: 16730995.

Navarro V, Delgado G. Two antimicrobial alkaloids from Bocconia arborea. J Ethnopharmacol. 1999 Aug;66(2):223-6. PMID: 10433482.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A0968

    Adrenocorticotropic Hormone (1-24), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • F5745

    Folic Acid

    Non-endogenous essential vitamin (B9), found in...

    ≥96%
  • Y0052

    Yangonin

    Dienolide kavalactone originally found in Piper...

    ≥98%
  • S3368

    S1RA

    σ1 antagonist.

    ≥99%
  • S041001

    SB-202190

    Highly selective inhibitor

    ≥99%
  • T0100

    10-Deacetyltaxol

    Taxane found in Taxus; microtubule depolymeriza...

    ≥98%
  • N3496

    Nizatidine

    Histamine H2 inverse agonist.

    ≥98%
  • E7758

    Etomidate

    GABA-A agonist.

    ≥99%
  • D0353

    Danofloxacin Mesylate

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • P3462

    Piperacillin

    β-lactam; penicillin binding protein inhibitor...

    ≥95%
  • P7000

    PR-619

    Deubiquitinating enzyme inhibitor.

    ≥98%
  • C2802

    CH5132799

    p110α PI3K inhibitor.

    ≥98%
  • T165133

    Tedizolid Phosphate

    Effective against gram-positive pathogens

    ≥98%
  • T162053

    Tebipenem pivoxil

    Prodrug

    ≥99%
  • S8012

    [Sar9]-Substance P

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • P1634

    Peimine

    Steroidal alkaloid found in Fritillaria; TRPV1 ...

    ≥98%
  • B6856

    5-Bromo-2′-Deoxyuridine

    Nucleoside (thymidine) analog.

    ≥98%
  • R5874

    Rosmarinic Acid

    Caffeic acid ester found in Melissa, Salvia, an...

    ≥98%
  • G1749

    Gemfibrozil

    Fibrate; PPARα agonist, enoyl-CoA reductase in...

    ≥98%
  • A9435

    Axitinib

    VEGFR inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only