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Alytesin

Product ID A4498
Cas No. 31078-12-3
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $74.10 In stock
2 mg $126.00 In stock
5 mg $222.50 In stock
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  • Product Info
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Alytesin is an antimicrobial peptide (AMP) originally found in the skin of amphibians. Alytesin decreases gastric acid secretion, decreasing food intake in vivo and exhibiting anorexigenic activity.

Product Info

Cas No.

31078-12-3

Purity

≥95%

Formula

C68H106N22O17S

Formula Wt.

1535.8

IUPAC Name

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4- methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]- 3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl- 1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1- oxopropan-2-yl]-2-[[(2S, 3R)-2-[[2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[[(2S)-5- oxopyrrolidine-2-carbonyl]amino]acetyl]amino]pentanoyl]amino]-4- methylpentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino] pentanediamide

Solubility

Soluble in water (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A4498 MSDS PDF

Info Sheet

A4498 Info Sheet PDF

References

König E, Zhou M, Wang L, et al. Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): implications for the evolution of frog skin defensive secretions. Toxicon. 2012 Nov;60(6):967-81. PMID: 22800568

Cline MA, Fouse DN, Prall BC. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. PMID: 18384875.

Guglietta A, Strunk CL, Irons BJ, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. Erratum in: Peptides 1987 May-Jun;8(3):579. PMID: 3841693.

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