• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ionomycin, Free Acid

Ionomycin, Free Acid

Product ID I5752
Cas No. 56092-81-0
Purity ≥98%, TLC, HPLC
Product Unit SizeCostQuantityStock
1 mg $65.40 In stock
5 mg $246.50 In stock
10 mg $385.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ionomycin is a polyether antibiotic that acts as a Ca2+ ionophore, modulating intracellular Ca2+ signaling to increase cytosolic Ca2+ levels. Ionomycin modulates Ca2+ signaling across many cell types and its depletion of intracellular Ca2+ stores may be linked to the induction of apoptosis.

Product Info

Cas No.

56092-81-0

Purity

≥98%, TLC, HPLC

Formula

C41H72O9

Formula Wt.

709.00

Chemical Name

(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic acid

IUPAC Name

11,19, 21-trihydroxy-22-[5-[5-(1-hydroxyethyl)-5-methyloxolan-2-yl]-5- methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10, 16-dienoic acid

Solubility

Soluble in DMSO (10 mg/mL), ethanol (10 mg/mL). Insoluble in water.

Appearance

Waxy Solid

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

I5752 MSDS PDF

Info Sheet

I5752 Info Sheet PDF

References

Müller MS, Obel LF, Waagepetersen HS, et al. Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry. Neurochem Res. 2013 Jun;38(6):1260-5. PMID: 23519933.

Dedkova EN, Sigova AA, Zinchenko VP. Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells. Membr Cell Biol. 2000;13(3):357-68. PMID: 10768486

Reynolds JE, Eastman A. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J Biol Chem. 1996 Nov 1;271(44):27739-43. PMID: 8910367.

Mason MJ, Grinstein S. Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes. Biochem J. 1993 Nov 15;296 ( Pt 1):33-9. PMID: 8250855.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B3458

    Biopterin

    Endogenous pterin coenzyme required for release...

    ≥98%
  • A7333

    Asiaticoside

    Triterpene found in Centella, prevents melanoge...

    ≥90%
  • G3358

    Ginkgolide ABC

    Mixture of Ginkgolides A, B and C, found in Gin...

    ≥98%
  • R2788

    RGW-611

    Morpholine derivative.

    ≥98%
  • S1604

    Secretin Acetate

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • D3202

    Diallyl Trisulfide

    Organosulfur found in garlic.

    ≥98%
  • D183734

    7-O-Desmethyl Rapamycin

    Rapamycin impurity

    ≥85%
  • A761003

    AT-7519 Hydrochloride

    ATP competitive CDK inhibitor.

    ≥98%
  • L0528

    LBH-589

    HDAC1/2/3/11 inhibitor.

    ≥98%
  • T0116

    2″,3″-Dihydrocephalomannine

    Cephalomannine derivative found in Taxus; poten...

    ≥96%
  • G8800

    GW-788388

    ALK5 (activin-like) antagonist.

    ≥97%
  • R8076

    Rutin Hydrate

    Flavonoid glycoside found in fruit, asparagus, ...

    ≥95%
  • I5315

    Indomethacin

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • C7692

    CTX IV (6-12)

    Snake venom cardiotoxin found in Naja naja atra...

    ≥98%
  • I7459

    1-Isothiocyanato-8-(methylsulfinyl)-octane

    ITC found in Nasturtium officinale (watercress)...

    ≥98%
  • M5753

    Monensin Sodium

    Polyether ionophore, autophagy inhibitor.

    ≥98%
  • G3557

    Ginsenoside Rh1

    Triterpene saponin found in species of Panax.

    ≥77%
  • S8248

    Sulfamethoxazole

    Sulfonamide; PABA inhibitor.

    ≥98%
  • C281006

    Chaetocin

    Chaetocin is naturally produced by Chaetomium s...

    ≥98%
  • V3276

    Vitamin E, Natural

    Antioxidant.

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only