Description
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
| Cas No. | 639052-78-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H13ClN2OS |
| Formula Wt. | 316.80 |
| IUPAC Name | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
| Solubility | 100mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.
SARS-CoV-2 inhibitor
Type A trichothecene mycotoxin produced by Fusa...
Pt-based DNA cross-linker.
Peptide found in molluscs, cardiomodulator.
Ras inhibitor.
Primarily targets HDAC1
5-HT3 antagonist.
Endogenous biogenic amine, norepinephrine-like ...
Anthracycline, DNA intercalator; topoisomerase ...
Found in Piper longum; TxA2 antagonist, ubiquit...
Phenothiazine; D1/2 and α1-adrenergic antagoni...
Prenylated phenolic terpene found in various pl...
Topoisomerase II inhibitor, RPA modulator.
MEK1/2 inhibitor.
HDAC inhibitor.
Podophyllotoxin derivative found in Podophyllum...
Semi-synthetic vinca alkaloid found in Catharan...
JAK1/2 inhibitor.
Endogenous neuropeptide hormone, lowers extrace...
Derivative of methyl caffeate, hydroxycinnamic ...