Description
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
| Cas No. | 639052-78-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H13ClN2OS |
| Formula Wt. | 316.80 |
| IUPAC Name | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
| Solubility | 100mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.
Potential anxiolytic.
Staurosporine derivative; PKC and FLT3 inhibito...
Macrolide; F1F0 ATP synthase inhibitor.
Hydroxycinnamic acid found in coffee, argan oil...
H+/K+ ATPase inhibitor.
EphB4 inhibitor.
DPP4 inhibitor.
Actinomycin derivative used to study apoptosis ...
Antitumor
Glucoside found in stone fruits and apples.
inhibits inflammatory signaling
Kv7 K+ channel activator, NMDA antagonist, GABA...
FIASMA; α1- and β1/2-adrenergic antagonist.
5-HT3 antagonist.
Nitrogen mustard and estradiol derivative; micr...
Allylbenzene found in spices and umbelliferous ...
Cyclohexanecarboxylic acid found in various pla...
Synthetic progestogen, orexigenic.
Endogenous steroid hormone involved in reproduc...
Endogenous opioid peptide; δOR and μOR agonis...