Description
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
| Cas No. | 639052-78-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H13ClN2OS |
| Formula Wt. | 316.80 |
| IUPAC Name | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
| Solubility | 100mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.
Polyphenol found in olive oil, antioxidant.
Organosulfide found in Allium; cholesterol synt...
Octapeptide derived from activity-dependent neu...
MET and GSK-3α/β inhibitor.
Semi-synthetic derivative of chlorophyll; food ...
Imidazole; 14-α demethylase inhibitor.
Mycotoxin.
Triadimefon metabolite; mutagen.
PDE and adenosine deaminase inhibitor.
Macrolide originally produced by Streptomyces; ...
NK1 antagonist.
Quinolone, antioxidant.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Microtubule polymerization inhibitor.
NSAID; COX-1/2 and lactate dehydrogenase inhibi...
Non-steroid; AR antagonist.
Stearoyl-coA desaturase 1 inhibitor.
Peptide hormone found in eels; GnRH agonist, we...
Phytoestrogen, isoflavone found in various plan...