Description
Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer and is one component of the “PCV” regimen.
Lomustine
Product ID L5648
Cas No. 13010-47-4
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 13010-47-4 |
|---|---|
| Purity | ≥98% |
| Formula | C9H16ClN3O2 |
| Formula Wt. | 233.70 |
| Chemical Name | N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea |
| IUPAC Name | 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea |
| Synonym | Belustine, Cecenu' CeeNU, CiNU |
| Melting Point | 90°C |
| Solubility | Soluble in ethanol (45 mg/mL), chloroform, acetone, DMSO (45 mg/mL). |
| Appearance | Yellowish Crystal |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.
Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.