• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Lonidamine

Lonidamine

Product ID L5658
Cas No. 50264-69-2
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $113.20 In stock
25 mg $202.70 In stock
100 mg $810.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Lonidamine inhibits glycolysis by inhibiting hexokinases; it exhibits anti-aging, anti-parasitic, and anti-fertility activities. Lonidamine increases lifespan in Caenorhabditis elegans, increasing stress resistance and promoting mitochondrial respiration by increasing levels of ROS. Lonidamine also displays antibiotic activity, causing death in Trypanosoma. In vivo, lonidamine increases testes weight and decreases sperm count and testosterone levels.

Product Info

Cas No.

50264-69-2

Purity

≥98%

Formula

C15H10Cl2N2O2

Formula Wt.

321.16

Chemical Name

1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid

IUPAC Name

1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid

Synonym

Diclondazolic acid, DICA, AF-1890, Doridamina.

Melting Point

207°C

Solubility

Soluble in methanol or acetic acid.

Appearance

White or off-white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L5658 MSDS PDF

Info Sheet

L5658 Info Sheet PDF

References

Schmeisser S, Zarse K, Ristow M. Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species. Horm Metab Res. 2011 Sep;43(10):687-92. PMID: 21932172.

Chambers JW, Fowler ML, Morris MT, et al. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1. Mol Biochem Parasitol. 2008 Apr;158(2):202-7. PMID: 18262292.

Traina ME, Guarino M, Natoli A, et al. Lonidamine affects testicular steroid hormones in immature mice. Toxicol Appl Pharmacol. 2007 May 15;221(1):95-101. PMID: 17442358.

Ditonno P, Battaglia M, Selvaggio O, et al. Clinical Evidence Supporting the Role of Lonidamine for the Treatment of BPH. Rev Urol. 2005;7 Suppl 7:S27-33. PMID: 16986058.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D1761

    15-Acetyl-deoxynivalenol

    Type A trichothecene mycotoxin produced by Fusa...

    ≥98%, TLC
  • M568264

    Mogroside IIe

    Triterpenoid

    ≥98%
  • L493400

    LMK-235

    Selective HDAC4 and HDAC5 inhibitor.

    ≥98%
  • H9763

    Hypoxanthine

    Endogenous purine derivative of xanthine.

    ≥98%
  • G4796

    Glycerol Monolaurate

    Surfactant found in coconut oil.

    ≥98%
  • D022705

    Darunavir

    HIV and AIDS

    ≥99%
  • R2511

    RGDC

    Peptide, used to study cell-surface binding; po...

    ≥95%
  • E6782

    S-Equol

    Isoflavone, phytoestrogen found in soy; ER agon...

    ≥99%
  • L8276

    Luteinizing Hormone Releasing Hormone

    Endogenous peptide hormone; GnRH agonist.

    ≥98%
  • I525138

    Indoximod

    Indoleamine 2,3-dioxygenase inhibitor.

    ≥98%
  • G0245

    Gallocatechin Gallate

    Polyphenol found in Camilla sinensis; HIV integ...

    ≥98%
  • M0009

    Macitentan

    ET-A/B antagonist.

    ≥99%
  • D1694

    Dexamethasone Acetate Monohydrate

    Steroid; glucocorticoid agonist.

    ≥98%
  • P9767

    Pyriproxyfen

    Juvenile insect hormone mimic.

    ≥95%
  • D183736

    19-O-Desmethoxy rapamycin

    Fermentation impurity

    ≥94%
  • M568266

    Mogroside IIIe

    Triterpenoid

    ≥98%
  • N8662

    NVP-BGJ398

    FGFR inhibitor.

    ≥98%
  • N3213

    Nidulal

    Sesquiterpene found in Nidula.

    ≥95%
  • E9317

    Exemestane

    Aromatase inhibitor.

    ≥97%
  • M3232

    Methylisoindigotin

    Indirubin derivative.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only