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Mastoparan 7

Mastoparan 7

Product ID M0272
Cas No. 145854-59-7
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $81.70 In stock
2 mg $138.90 Please Inquire
5 mg $245.30 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Mastoparan 7 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps that activates Gi/o GPCRs, increasing release of downstream signaling messengers such as cAMP, atrial natriuretic factor, and ATP. Mastoparan 7 restores neurotransmitter release from spinal cord cells treated with botulinum toxin serotype A. Additionally, mastoparan 7 activates phospholipase A2 (PLA2).

Product Info

Cas No.

145854-59-7

Purity

≥95%

Formula

C67H124N18O15

Formula Wt.

1421.85

IUPAC Name

(2S)-N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]butanediamide

Synonym

Mas7

Solubility

Soluble in DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

M0272 MSDS PDF

Info Sheet

M0272 Info Sheet PDF

References

Zhang P, Ray R, Singh BR, et al. Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model. Toxicon. 2013 Dec 15;76:37-43. PMID: 24047963.

Sprague RS, Bowles EA, Achilleus D, et al. A selective phosphodiesterase 3 inhibitor rescues low PO2-induced ATP release from erythrocytes of humans with type 2 diabetes: implication for vascular control. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2466-72. Erratum in: Am J Physiol Heart Circ Physiol. 2012 Jan;302(1):H378. PMID: 21963837.

Sprague R, Bowles E, Stumpf M, et al. Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi. Pharmacol Rep. 2005;57 Suppl:222-8. PMID: 16415502.

Bensimon M, Chang AI, de Bold ML, et al. Participation of G proteins in natriuretic peptide hormone secretion from heart atria. Endocrinology. 2004 Nov;145(11):5313-21. PMID: 15308619.

Custom Order

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