• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Methyldopa Sesquihydrate

Methyldopa Sesquihydrate

Product ID M1779
Cas No. 41372-08-1
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $58.20 In stock
5 g $81.70 In stock
10 g $145.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Methyldopa exhibits antihypertensive and sedative activities. In circulation, methyldopa is metabolized to α-methylnorepinephrine by dopamine β-hydroxylase, which activates α2-adrenergic receptors, acting as a sympatholytic and inhibiting the sympathetic nervous system. This compound also inhibits DOPA decarboxylase, decreasing production of dopamine, norepinephrine, and epinephrine. In animal models, methyldopa exhibits NO-dependent sedative activity similar to that of clonidine.

Product Info

Cas No.

41372-08-1

Purity

≥98%

Formula

C10H13NO4 • 3/2H2O

Formula Wt.

238.24

Chemical Name

3-Hydroxy-α-methyl-L-tyrosine sesquihydrate

IUPAC Name

(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;trihydrate

Synonym

Methyl-L-DOPA, MK-351, Hyperax

Melting Point

>300°C (dec.)

Solubility

Soluble in dilute mineral acids and water (10mg/mL, pH 5.0). Insoluble in organic solvents.

Appearance

White or yellowish white, crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

M1779 MSDS PDF

Info Sheet

M1779 Info Sheet PDF

References

Sucak A, Kanat-Pektas M, Gungor T, et al. Leptin levels and antihypertensive treatment in preeclampsia. Singapore Med J. 2010 Jan;51(1):39-43. PMID: 20200774.

Soares de Moura R, Rios AA, et al. The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine. Anesth Analg. 2001 Nov;93(5):1217-21. PMID: 11682401.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D3356

    Diosmetin

    O-methylated flavone found in vetch and various...

    ≥98%
  • C9615

    Cyclosporin B

    Cyclic peptide; calcineurin inhibitor.

    ≥95%
  • P8118

    Puerarin

    Isoflavone daidzein derivative found in Puerari...

    ≥96%
  • S8169

    Suramin Hexasodium

    RyR agonist, SIRT, telomerase, P2Y, GPCR inhibi...

    ≥98%
  • R0154

    Ranolazine Dihydrochloride

    Nav1.7 and Nav1.8 N1+ channel blocker.

    ≥98%
  • A7309

    Ascorbyl Palmitate

    Fat-soluble vitamin C derivative.

    ≥95%
  • A985130

    AZD-7762

    CHK1 inhibitor.

    ≥98%
  • T5846

    Tolfenamic Acid

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • T7133

    Trimetazidine Dihydrochloride

    Long-chain 3-ketoacyl-CoA thiolase inhibitor, p...

    ≥99%
  • G5874

    Gossypol

    Polyphenol found in Gossypium; calcineurin and ...

    ≥98%
  • L8010

    D-Luciferin Potassium

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • O9397

    Oxytetracycline Hydrochloride

    Tetracycline; protein translation inhibitor.

    ≥96%
  • Q8135

    Quinestrol

    Synthetic steroid hormone, estrogen analog, use...

    ≥98%
  • G4480

    Glucagon, human

    Endogenous peptide hormone, counteracts insulin...

    ≥95%
  • T1978

    Tetrahydroberberine

    Isoquinoline alkaloid found in Corydalis; 5-HT1...

    ≥98%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • A5061

    Ampalex

    Benzylpiperidine; AMPA potentiator.

    ≥98%
  • S1848

    Se-Methylseleno-L-cysteine

    Found in plants in Astragalus, Allium, and Bras...

    ≥98%
  • K1655

    Kenpaullone

    GSK-3β, HGK, and CDK inhibitor.

    ≥95%
  • T0008

    Tacrolimus

    Calcineurin inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only