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Ampalex

Product ID A5061
Cas No. 154235-83-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $88.60 In stock
5 mg $130.40 In stock
10 mg $191.40 In stock
25 mg $375.30 In stock
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  • Product Info
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  • Description
  • Product Info
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Description

Ampalex is a benzylpiperidine AMPA receptor potentiator. It exhibits antipsychotic activity and may also show cognition enhancing and neuroprotective benefits. Ampalex modulates fast synaptic plasticity and memory process in various models. This compound also improves cognitive function in animal models of schizophrenia.

Product Info

Cas No.

154235-83-3

Purity

≥98%

Formula

C14H15N3O

Formula Wt.

241.29

IUPAC Name

1-Piperidinyl(6-quinoxalinyl)methanone

Synonym

CX-516, BDP-12, Benzoyl-Piperidine-12, SPD-420

Solubility

H2O: 5 mg/mL DMSO 40 mg/ml

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A5061 MSDS PDF

Info Sheet

A5061 Info Sheet PDF

References

O'Neill MJ, Witkin JM. AMPA receptor potentiators: application for depression and Parkinson's disease. Curr Drug Targets. 2007 May;8(5):603-20. PMID: 17504104.

Olsen CK, Kreilgaard M, Didriksen M. Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats. Pharmacol Biochem Behav. 2006 Jun;84(2):259-65. PMID: 16782180.

O'Neill MJ, Bleakman D, Zimmerman DM, et al. AMPA receptor potentiators for the treatment of CNS disorders. Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):181-94. PMID: 15180479.

Danysz W. CX-516 (Cortex Pharmaceuticals Inc). IDrugs. 1999 Aug;2(8):814-22. PMID: 16127658.

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