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Fibrinogen γ-chain Dodecapeptide

Product ID F3205
Cas No. 89105-94-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $111.30 In stock
2 mg $185.40 In stock
5 mg $367.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fibrinogen γ-chain dodecapeptide binds glycoprotein GP IIb/IIIa on platelets, exhibiting hemostatic, pro-thrombotic activity and enhancing thrombus formation. This peptide rescues thrombocytopenic rabbits from liver hemorrhage and is clinically used as a platelet substitute.

Product Info

Cas No.

89105-94-2

Purity

≥95%

Formula

C50H80N18O16

Formula Wt.

1189.29

Synonym

Fibrinogen gamma-chain dodecapeptide, Fibrinogen Binding Inhibitor Peptide

Solubility

Soluble in water (2 mg/mL).

Appearance

White powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

F3205 MSDS PDF

Info Sheet

F3205 Info Sheet PDF

References

Tokutomi K, Tagawa T, Korenaga M, et al. Ability of fibrinogen γ-derived dodecapeptides with different sequences to bind to rat platelets. Int J Pharm. 2012 Nov 15;438(1-2):296-301. PMID: 22985603.

Nishikawa K, Hagisawa K, Kinoshita M, et al. Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage. J Thromb Haemost. 2012 Oct;10(10):2137-48. PMID: 22905905.

Okamura Y, Maekawa I, Teramura Y, et al. Hemostatic effects of phospholipid vesicles carrying fibrinogen gamma chain dodecapeptide in vitro and in vivo. Bioconjug Chem. 2005 Nov-Dec;16(6):1589-96. PMID: 16287259.

Custom Order

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