Description
Metyrapone, an adrenal steroid synthesis Inhibitor that inhibits the steroid 11-beta-monooxygenase enzyme.
Product Unit Size | Cost | Quantity | Stock |
---|
Metyrapone, an adrenal steroid synthesis Inhibitor that inhibits the steroid 11-beta-monooxygenase enzyme.
Cas No. | 54-36-4 |
---|---|
Purity | ≥98% |
Formula | C14H14N2O |
Formula Wt. | 226.27 |
Chemical Name | 2-Methyl-1,2-di-3-pyridyl-1-propanone |
IUPAC Name | 2-methyl-1,2-dipyridin-3-ylpropan-1-one |
Synonym | Metopirone; Methopyrapone; Metopiron; Methapyrapone; Methopirapone; Methopyrinine; Methopyrone; Metopyrone |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
Info Sheet |
---|
R Sampath-Kumar, M Yu, M W Khalil, K Yang. Metyrapone is a competitive inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 reductase. J Steroid Biochem Mol Biol. 1997, 62:195-9.
M Fassnacht, S Hahner, F Beuschlein, et al. New mechanisms of adrenostatic compounds in a human adrenocortical cancer cell line. Eur J Clin Invest. 2000, 30:76-82.
DNA alkylator.
Corticosteroid
Tyrphostin; IGF-1R inhibitor.
Alters membrane permeability and Ca2+ signaling...
Antioxidant.
c-Met inhibitor.
ROCK1/2 inhibitor.
TNKS1/2 inhibitor.
Synthesis impurity
PKC and PKD activator, carcinogen.
Carotenoid found in shrimp, salmon, and algae.<...
Acridine derivative, DNA intercalator; topoisom...
EGFR inhibitor.
nNOS inhibitor.
Fluoroquinolone; topoisomerase IV and bacterial...
Sulforaphane-cysteine conjugate.
Ca2+-sensing receptor agonist.
Peptide, involved in feeding behavior and insul...
Synthetic steroid hormone used in HRT; SERM, PR...
EGFR inhibitor.