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N(α),N(α)-Dimethyl-L-Arginine Ammonium

N(α),N(α)-Dimethyl-L-Arginine Ammonium

Product ID A6828
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $35.50 Please Inquire
25 mg $73.70 Please Inquire
100 mg $246.20 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nα,Nα-Dimethyl-L-arginine is also known as asymmetrical dimethyl-L-arginine (ADMA). This compound is an endogenous inhibitor of NOS and is involved in the regulation of the water/sodium balance. High levels of ADMA are associated with obesity, atherosclerosis, renal disease, and coronary artery disease. ADMA aggravates gastric mucosal lesions in vivo, increasing levels of TNF-α and suppressing gastric blood flow.

Product Info

Purity

≥98%

Formula

C8H18N4O2 • NH3

Formula Wt.

219.28

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A6828 MSDS PDF

Info Sheet

A6828 Info Sheet PDF

References

Mauricio MD, Aldasoro M, Ortega J, et al. Endothelial dysfunction in morbid obesity. Curr Pharm Des. 2013;19(32):5718-29. PMID: 23448493.

Szlachcic A, Krzysiek-Maczka G, Pajdo R, et al. The impact of asymmetric dimethylarginine (ADAMA), the endogenous nitric oxide (NO) synthase inhibitor, to the pathogenesis of gastric mucosal damage. Curr Pharm Des. 2013;19(1):90-7. PMID: 22950506.

Twardowski ZJ. Sodium, hypertension, and an explanation of the "lag phenomenon" in hemodialysis patients. Hemodial Int. 2008 Oct;12(4):412-25. PMID: 19090863.

Surdacki A. L-arginine analogs--inactive markers or active agents in atherogenesis? Cardiovasc Hematol Agents Med Chem. 2008 Oct;6(4):302-11. PMID: 18855643.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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