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Small Cardioactive Peptide B

Small Cardioactive Peptide B

Product ID S1061
Cas No. 84746-43-0
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $98.40 In stock
2 mg $167.80 In stock
5 mg $294.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Small cardioactive peptide B (SCPB) is a peptide co-transmitter intrinsic to motor neurons that controls feeding behavior and muscle movement in molluscs such as species of Lymnea, Aplysia, and Clione. SCPB acts at the neuromuscular synapse, increasing cAMP; here, this peptide facilitates connection between cholinergic inhibitory neurons and sensory neurons. SCPB also controls feeding behavior, increasing feeding arousal.

Product Info

Cas No.

84746-43-0

Purity

≥95%

Formula

C52H80N14O11S2

Formula Wt.

1141.43

IUPAC Name

(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]butanediamide

Synonym

SCPB

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S1061 MSDS PDF

Info Sheet

S1061 Info Sheet PDF

References

Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Norekian TP, Satterlie RA. Small cardioactive peptide B increases the responsiveness of the neural system underlying prey capture reactions in the pteropod mollusc, Clione limacina. J Exp Zool. 1994 Oct 1;270(2):136-47. PMID: 7999153.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

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