LKT Labs

Biochemicals for Life Science Research

Neuromedin B, pig

Neuromedin B, pig

Product ID N1980
Cas No. 87096-84-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $131.00 In stock
2 mg $223.00 In stock
5 mg $392.00 In stock
Bulk Quote

Quicklinks

Description

Neuromedin B is an endogenous bombesin-related peptide that binds BB receptors, displaying the greatest affinity for the BB1 receptor. Neuromedin B exhibits anorexigenic and cardiomodulatory activities, decreasing food intake, inducing bradycardia, and slowing gastric emptying in vivo. Neuromedin B also activates ERK1/2 signaling, increasing osteoblast proliferation and bone formation. Additionally, neuromedin B increases secretion of luteinizing hormone (LH) and gonadotropin-releasing hormone (GnRH) in vitro and in vivo.

Product Info

Cas No.

87096-84-2
Purity

≥95%
Formula

C52H73N15O12S
Formula Wt.

1132.3
Chemical Name

1-glycine-2-L-asparagine-3-L-leucine-4-de-L- glutamine-7-L-threonine-Ranatensin
IUPAC Name

(2S)-2-[(2-aminoacetyl)amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S, 3R)-1-[[2-[[(2S)-1-[[1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl] amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1- oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino] -1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4- methyl-1-oxopentan-2-yl]butanediamide
Solubility

Soluble in water (1 mg/mL).
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

N1980 MSDS PDF
Info Sheet

N1980 Info Sheet PDF

References

Boughton CK, Patel SA, Thompson EL, et al. Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats. Regul Pept. 2013 Nov 10;187:6-11. PMID: 24120470.

Saito H, Nakamachi T, Inoue K, et al. Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts. J Endocrinol. 2013 Apr 15;217(2):141-50. PMID: 23428580.

Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B1979

    Betulinic Acid

    Pentacyclic triterpene.

    ≥99%
  • L0400

    LB-100

    PP2A inhibitor.

    ≥98%
  • O9398

    Oxymetazoline Hydrochloride

    Imidazoline derivative; α1-adrenergic agonist,...

    ≥98%
  • T3134

    Thiostrepton

    Thiazole; proteasome inhibitor, protein translo...

    ≥97%, HPLC
  • I544766

    Intepirdine

    Selective 5-HT6 receptor antagonist

    ≥98%
  • N4972

    NMS-873

    Valosin-containing protein inhibitor.

    ≥98%
  • B3573

    Bisdemethoxycurcumin

    Curcumin derivative; DNMT1 and α-amylase inhib...

    ≥98%
  • M568266

    Mogroside IIIe

    Triterpenoid

    ≥98%
  • C0369

    Cardiogenol C Hydrochloride

    Induces cardiomyogenic effects in pluripotent c...

    ≥98%
  • C0151

    α-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥95%
  • D5792

    Doxofylline

    Xanthine derivative; PDE inhibitor.

    ≥98%
  • M4455

    MLN-2238

    Proteasome inhibitor, miR33b modulator.

    ≥95%
  • T982698

    L-Tyrosine disodium salt

    Amino acid precursor of dopamine.

    ≥98%
  • B560000

    RAD51 inhibitor, B02

    RAD51 inhibitor.

    ≥98%
  • L186860

    Levomefolic acid calcium salt

    Folic acid derivative

    ≥98%
  • L5862

    Lopinavir

    HIV protease inhibitor, SERCA inhibitor.

    ≥98%
  • B0397

    BAY80-6946 Hydrochloride

    pan-PI3K inhibitor

    ≥98%
  • I7359

    1-Isothiocyanato-8-(methylsulfenyl)-octane

    ITC, erucin analog.

    ≥98%
  • I5315

    Indomethacin

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • T1298

    TDZD-8

    GSK-3β inhibitor.

    ≥98%