Description
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
| Cas No. | 212779-48-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H19ClN6O |
| Formula Wt. | 346.81 |
| Chemical Name | 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine |
| IUPAC Name | 2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol |
| Synonym | Compound 52 |
| Solubility | 10 mM in DMSO, 50 mg/mL in methylene chloride: |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gray NS, Wodicka L, Thunnissen AM, et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8. PMID: 9677190.
H+/K+ ATPase and ROCK-2 inhibitor.
BRD2/3/4 inhibitor.
CDK2 inhibitor
Peptide, used to study cell-surface binding; po...
Histamine H1-antagonist
Endogenous calcitonin-family peptide, involved ...
CDK4/6 inhibitor.
FGFR inhibitor.
Steroid; AR antagonist.
Semi-synthetic derivative of chlorophyll; food ...
Islet β cell proliferation stimulator.
BRD binding agent, CDK1/2/5/9 inhibitor.
Endogenous heptapeptide; P2X3 and N-formylpepti...
Aminoglycoside; protein translation inhibitor.<...
STING inhibitor
Fetal hemoglobin stimulator; ribonucleotide red...
PRMT5 inhibitor
Diterpene found in brewed, unfiltered coffee; F...
Diterpene found in Taxus, used to synthesize ta...
HDAC inhibitor. May reduce blood pressure in hy...