Description
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
| Cas No. | 212779-48-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H19ClN6O |
| Formula Wt. | 346.81 |
| Chemical Name | 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine |
| IUPAC Name | 2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol |
| Synonym | Compound 52 |
| Solubility | 10 mM in DMSO, 50 mg/mL in methylene chloride: |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gray NS, Wodicka L, Thunnissen AM, et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8. PMID: 9677190.
Non-depolarizing NMJ blocker; nAChR and M2/3 mA...
Non-opioid analgesic.
Alkaloid found in Stephania.
MET inhibitor.
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
Found in Polygata tennifolia.
Smoothened agonist.
Caspase 9 substrate.
Recombinant HIV-1 glycoprotein antigen fragment...
Sesquiterpene lactone found in Saussurea.
MEK1/2 and Raf inhibitor.
Antimicrobial peptide found in Trichoderma, ind...
Cembranoid found in Sarcophyton.
InsR and IGF-1R inhibitor.
Akt inhibitor.
Peptide, substance P analog; NK agonist.
beta-catenin inhibitor
ALK and IGF-1R inhibitor.
Unlikely to reverse Alzheimer’s
Antimicrobial peptide found in bee and wasp ven...