Description
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
| Cas No. | 212779-48-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H19ClN6O |
| Formula Wt. | 346.81 |
| Chemical Name | 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine |
| IUPAC Name | 2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol |
| Synonym | Compound 52 |
| Solubility | 10 mM in DMSO, 50 mg/mL in methylene chloride: |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gray NS, Wodicka L, Thunnissen AM, et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8. PMID: 9677190.
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