Description
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
| Cas No. | 212779-48-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H19ClN6O |
| Formula Wt. | 346.81 |
| Chemical Name | 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine |
| IUPAC Name | 2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol |
| Synonym | Compound 52 |
| Solubility | 10 mM in DMSO, 50 mg/mL in methylene chloride: |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gray NS, Wodicka L, Thunnissen AM, et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8. PMID: 9677190.
Alkaloid found in Catharanthus, precursor in sy...
Mycotoxin produced by Aspergillus; actin polyme...
Isoquinoline alkaloid found in Corydalis, Phell...
Butyrophenone; σ2 agonist, α1-adrenergic, D2,...
Neuropeptide hormone found in insects, involved...
Fat-soluble vitamin C derivative.
Endogenous purine derivative of xanthine.
Mycotoxin produced by Aspergillus; actin polyme...
Wortmannin analog; PI3K inhibitor.
PI3K and mTOR inhibitor.
NSAID; COX-1/2 inhibitor.
Alkaloid found in black and long peppers; TRPV1...
Alkaloid found in Stephania.
Triterpene saponin originally found in Bolboste...
GHB agonist, D2/3 antagonist.
Cysteine conjugate of benzyl isothiocyanate (BI...
Tankyrase inhibitor.
Purine nucleotide analog, mercaptiopurine prodr...
Synthetic cyclic dinucleotide agonist of STING....
RAD51 inhibitor.