• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Nocodazole

Nocodazole

Product ID N5409
Cas No. 31430-18-9
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $102.00 In stock
50 mg $357.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nocodazole is an inhibitor of microtubule polymerization that exhibits anticancer and anti-parasitic activities. Nocodazole induces depolarization of the mitochondrial membrane, caspase activation, PARP cleavage, and apoptosis in chronic lymphocytic leukemia (CLL) cells. Nocodazole also kills Alveococcus larvocysts in vivo.

Product Info

Cas No.

31430-18-9

Purity

≥98%

Formula

C14H11N3O3S

Formula Wt.

301.32

Chemical Name

[5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]- carbamic acid methyl ester

IUPAC Name

methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate

Synonym

Oncodazole, R 17934

Melting Point

300°C (dec)

Solubility

Soluble in DMSO. Insoluble in water.

Appearance

Off-white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Blue Ice

Downloads

MSDS

N5409 MSDS PDF

Info Sheet

N5409 Info Sheet PDF

References

Shkoliar NA, Kukhaleva IV, Legon'kov IuA, et al. Study of the therapeutic activity of nocodazole on experimental models of larval alveococcosis. Med Parazitol (Mosk). 2013 Apr-Jun;(2):20-7. PMID: 24003517.

Beswick RW, Ambrose HE, Wagner SD. Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression. Leuk Res. 2006 Apr;30(4):427-36. PMID: 16162358.

Rahajeng J, Giridharan SS, Naslavsky N, Caplan S. Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors. J Biol Chem. 2010 Oct 15;285(42):31918-31922. PMID: 20801876.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C324091

    Ciclesonide

    Corticosteroid

    ≥98%
  • L8010

    D-Luciferin Potassium

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • C691325

    Cridanimod

    STING agonist

    ≥99%
  • B5874

    Bosutinib

    Src and Abl inhibitor.

    ≥98%
  • B3275

    Bis(3,5-dibromosalicyl) Succinate

    Aspirin analog; hemoglobin chain cross-linker.<...

    ≥95%
  • C4274

    CKS-17

    Synthetic peptide, retroviral envelope protein ...

    ≥95%
  • O5212

    Ondansetron Hydrochloride Dihydrate

    5-HT3 antagonist.

    ≥98%
  • H174466

    Helvolic acid

    A fungal metabolite that inhibits protein synth...

    ≥98%
  • P2819

    6-Phenylhexa-3,5-dien-2-one

    Minor kavalactone originally found in Piper met...

    ≥96%
  • E5241

    Met-Enkephalin

    Endogenous opioid peptide; δOR and μOR agonis...

    ≥95%
  • C0275

    Castanospermine

    O-GlcNAcase inhibitor.

    ≥98%
  • F3354

    Finasteride

    Steroid 5-α-reductase inhibitor.

    ≥98%
  • C9673

    Cysteamine Hydrochloride

    Aminothiol, CoA component; ulcer inducer.

    ≥99%
  • E6257

    Epothilone B

    Microtubule depolymerization inhibitor.

    ≥98%
  • R5773

    Rosiglitazone

    Thiazolidinedione; PPARγ agonist.

    ≥99%
  • L1869

    Lercanidipine Hydrochloride

    Calcium channel blocker.

    ≥98%
  • A0918

    N-Acetyl-L-Cysteine

    Cysteine derivative, antioxidant, ROS scavenger...

    ≥98%
  • D1859

    2-Deoxy-D-glucose

    Glucose metabolism inhibitor, N-linked glycosyl...

    ≥99%
  • N5210

    Nociceptin

    Endogenous neuropeptide, involved in opioid sig...

    ≥98%
  • H9613

    N-(4-Hydroxyphenyl)retinamide

    Retinol (vitamin A) analog, binds RBP4; Des1 in...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only