Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Product Unit Size | Cost | Quantity | Stock |
---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Cas No. | 58131-57-0 |
---|---|
Purity | ≥98% |
Formula | C11H13N5O4 |
Formula Wt. | 279.25 |
Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
Appearance | Orange to red solid |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Mas antagonist.
Isoflavone found in legumes such as soy.
(S) isomer of omeprazole; H+/K+ ATPase and MAO-...
Immunomodulator; teratogen.
Naturally-ocurring neurtral cyclic ionophore, m...
Steroidal saponin found in Dioscorea.
N-acetyl cysteine conjugate of phenethylisothio...
SERM, androgen modulator.
CHK1 inhibitor.
NSAID; COX-1/2 inhibitor.
H+/K+ ATPase inhibitor.
Iridoid glucoside found in Cornus officialis; Î...
Piroxicam prodrug, NSAID; COX-1/2 inhibitor.
AurK, FLT3, Abl inhibitor.
Peptide, bee venom toxin; SK2/3/4 K+ channel bl...
Microtubule polymerization inhibitor.
Macrocyclic lactone.
ITC found in cruciferous vegetables.
principal metabolic product of COX-2
Endogenous peptide hormone inolved in gastric e...