Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Protein translation inhibitor.
Voltage-gated K+ channel blocker.
Nitrosourea-amino sugar conjugate, DNA cross-li...
MEK inhibitor.
Naturally occurring sesteterpenoid.
Endogenous calcitonin-family peptide, involved ...
Antioxidant shown to improve renal function.
p53 inhibitor
Islet α/β cell proliferation stimulator.
Active metabolite of losartan
Non-endogenous essential amino acid found in me...
Antineoplastic immunomodulator.
Geldanamycin derivative; HSP90 inhibitor.
Imidazole; 14-α demethylase inhibitor.
Synthetic steroid hormone used in HRT; SERM, PR...
Antimicrobial peptide found in Hyalophora cecro...
Ellagic acid derivative produced by gut microfl...
Labdane diterpene found in Andrographolis; cNOS...
CDK1/2 inhibitor.
Endogenous peptide hormone, involved in stress ...