Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Product Unit Size | Cost | Quantity | Stock |
---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Cas No. | 58131-57-0 |
---|---|
Purity | ≥98% |
Formula | C11H13N5O4 |
Formula Wt. | 279.25 |
Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
Appearance | Orange to red solid |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Fat-soluble vitamin C derivative.
Endogenous neuropeptide hormone; somatostatin a...
Synthesis intermediate
Synthetic nitrile compound
Triazolothienodiazepine, JQ-1 derivative; BRD i...
Salicylic acid prodrug, NSAID; weak COX-1/2 inh...
Polyene macrolide, induces pore formation in fu...
Mast cell stabilizer; histamine H1/2/3 antagoni...
Endogenous peptide hormone, involved in secreti...
Cap-dependent endonuclease inhibitor
Polyphenolic compound present in black tea.
Cysteine-ITC conjugate, antioxidant.
Synthetis peptide, melanocortin analog; MCR ago...
Long chain acylcarnitine involved in fatty acid...
Pt-based DNA cross-linker.
Vitamin E analog, antioxidant.
p110γ PI3K inhibitor.
Steroid; glucocorticoid agonist.
HDAC inhibitor.
Statin; HMG-CoA reductase inhibitor.