Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
NSAID; COX-1/2 inhibitor.
Microtubule polymerization inhibitor, potential...
2-methyl-1,4-naphthoquinone derivative
Spirodihydrobenzofuranlactam
Cyclic hexadepsipeptide mycotoxin produced by C...
Glutathione-ITC conjugate, antioxidant.
A fungal metabolite that inhibits protein synth...
Recombinant chimeric protein containing Trepone...
ALK inhibitor.
Synthetic peptide hormone, PTH analog; PTH1R ag...
Polyether Ca2+ ionophore.
ITC found in cruciferous vegetables.
HPGDS inhibitor.
CHK1 inhibitor.
EGFR inhibitor.
Flavanol found in Camilla (green tea); AhR ant...
Alkaloid found in Sophora.
Flavonoid found in various plant sources.
Taxane found in Taxus; potential microtubule de...
Phytoestrogen, isoflavone found in various plan...