Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Alkaloid found in Corydalis and Stephania; D1/2...
c-MET inhibitor.
Antioxidant, vitamin E derivative found in vege...
Alpha blocker and vasoactive agent.
Pneumonia antigen
NNK precursor found in tobacco smoke; carcinoge...
Flavonoid found in Epimedium sagittatum.
Cembranoid found in Sarcophyton.
Fermentation impurity
Antimicrobial peptide found in bee and wasp ven...
ALK and IGF-1R inhibitor.
AChE inhibitor, F0F1-ATP synthase modulator.
PORCN inhibitor.
Cap-dependent endonuclease inhibitor
MEK1/2 inhibitor.
CDK2 inhibitor.
Sirtuin inhibitor and iron chelator.
FIASMA; α1- and β1/2-adrenergic antagonist.
Endogenous opioid peptide; μOR agonist.
Glycoprotein IIb/IIIa inhibitor.