Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Cholesterol ester transfer protein inhibitor.
Peptide, vSrc-induced cytokine.
Triterpenoid
Deubiquitinating enzyme inhibitor.
Pyridopyrimidinone; PI3K and mTOR inhibitor.
Cephalosporin analogue
CDK inhibitor.
MDM2 inhibitor.
Recombinant HIV-1 glycoprotein antigen fragment...
Synthetic kahweol derivative.
Sesquiterpene found in various plant sources. <...
Ellagic acid derivative produced by gut microfl...
Akt inhibitor.
Antioxidant; Nrf2 activator.
Peptide used to measure in vitro calcineurin ac...
SERT inhibitor.
ALK and IGF-1R inhibitor.
Thiamine/vitamin B derivative, antioxidant.
Anxiolytic-like agent that stimulates angiogene...
Phenol found in Zingiber; 5-HT3 antagonist.