Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Endogenous peptide fragment, immunostimulant; ...
Endogenous peptide, cleavage product of angiote...
Tropane alkaloid found in Solanaceae plants; M1...
Sulforaphane-cysteine conjugate.
Sesquiterpene alcohol found in various essentia...
Lignan found in Magnolia; GABA-A potentiator.
5-FU prodrug; thymidylate synthase inhibitor.
Peptide, involved in paracrine and autocrine ce...
TRPC5, NS4B, histamine H1 inhibitor.
AurKA/B inhibitor.
TRPV4 agonist
Abl, PDGFR, EphR, Src, k-Kit, FYN, LCK, HCK inh...
Imidazoline and α2-adrenergic agonist, Nav1.7 ...
Cephalomannine derivative found in Taxus; poten...
Selective CDK2 inhibitor.
Polypeptide; serine protease inhibitor.
Diterpene found in brewed, unfiltered coffee; F...
Bufanolide steroid found in Bufo arenarum;VEGFR...
Ellagic acid derivative produced by gut microfl...