Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Endogenous peptide, involved in hormone regulat...
Loop diuretic; NKCC symporter and KCC2 co-trans...
Mycotoxin produced by Alternaria; photosynthesi...
Dihydrofolate reductase inhibitor.
Endogenous neurotransmitter; GABA agonist.
Peptide hormone found in eels; GnRH agonist, we...
β-adrenergic antagonist, voltage-gated Na+ and...
Resveratrol prodrug; potential SIRT1 activator....
Triazole; 14-α demethylase and aromatase inhib...
Inhibitor of EGFR, HER2, and HER3.
Pt-based DNA cross-linker.
Pyrrolopyrimidine; Akt inhibitor.
Diterpene found in Salvia.
ITC found in cruciferous vegetables; HDAC inhib...
Endogenous peptide involved in vascular contrac...
Peptide, inactive mastoparan analog used to mea...
Imidazoline and α2-adrenergic agonist, Nav1.7 ...
Alkaloid found in Cephalotaxus; ribosomal prote...
Anthracycline, DNA intercalator; topoisomerase ...
Semi-synthetic avermectin; GABA potentiator.