Description
Oxazolidine Cabazitaxel is an impurity in the synthesis of the anti-cancer compound cabazitaxel.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Oxazolidine Cabazitaxel is an impurity in the synthesis of the anti-cancer compound cabazitaxel.
| Cas No. | 1373171-12-0 |
|---|---|
| Purity | ≥95% |
| Formula | C48H61NO14 |
| Formula Wt. | 875.41 |
| IUPAC Name | 5-O-[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-2-benzoyloxy-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-15-yl] 3-O-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate |
| Synonym | (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) ester |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.
Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.
Staurosporine analog; PKC inhibitor, TrkA/B ant...
Isoleucyl-tRNA synthase inhibitor, osteoclast p...
Casein kinase 2 inhibitor.
Endogenous APP peptide cleavage product, primar...
Micronuclei formation inducer, antimitotic, oxi...
Phenyl hydrazide; neuronal oxidative stress inh...
Triazolothienodiazepine, JQ-1 derivative; BRD i...
PAK4 inhibitor.
Src and Abl inhibitor.
Isoflavone, phytoestrogen found in soy; ER agon...
FIASMA, mAChR, 5-HT2/3/6/7, α1/2-adrenergic an...
Corticosteroid
Diaminoquinazoline derivative.
Diterpene alkaloid found in Aconitum; voltage-g...
Mycotoxin.
Tropane alkaloid found in Solanaceae plants; α...
Inert clozapine analog, activates specialized G...
Nucleoside (adenosine) analog found in Tethyra ...
Polyanionic sulfated glycosaminoglycan, encogen...
Alkaloid found in Catharanthus, precursor in sy...