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Oxazolidine Cabazitaxel

Oxazolidine Cabazitaxel

Product ID C002045
Cas No. 1373171-12-0
Purity ≥95%
Product Unit SizeCostQuantityStock
10 mg $376.40 In stock
50 mg $973.40 In stock
250 mg $3,244.70 In stock
500 mg $4,704.80 Please Inquire
Bulk Quote

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  • Description
  • Product Info
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  • Description
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  • References
  • Custom Order

Description

Oxazolidine Cabazitaxel is an impurity in the synthesis of the anti-cancer compound cabazitaxel.

Product Info

Cas No.

1373171-12-0

Purity

≥95%

Formula

C48H61NO14

Formula Wt.

875.41

IUPAC Name

5-O-[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-2-benzoyloxy-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-15-yl] 3-O-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Synonym

(4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) ester

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

C002045 Info Sheet PDF

References

Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.

Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.

Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.

Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.

Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.

Custom Order

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