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Phyllolitorin

Phyllolitorin

Product ID P2992
Cas No. 87734-77-8
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $98.40 Please Inquire
1 mg $167.80 Please Inquire
2.5 mg $294.60 Please Inquire
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Phyllolitorin is a bombesin-related amphibian nonapeptide. Phyllolitorin induces contractions in urinary bladder smooth muscle and may play a role in lung branching morphogenesis. In mammals, phyllolitorin binds the gastrin-releasing peptide (GRP)-preferring bombesin receptor and the neuromedin B-preferring bombesin receptor. Phyllolitorin also elicits grooming and scratching behavior in mammalian animal models.

Product Info

Cas No.

87734-77-8

Purity

≥95%

Formula

C49H69N11O11S

Formula Wt.

1020.24

IUPAC Name

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-5-oxopyrrolidine-2-carboxamide

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

P2992 Info Sheet PDF

References

Lin JT, Coy DH, Mantey SA, et al. Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Eur J Pharmacol. 1995 Dec 27;294(1):55-69. PMID: 8788416.

King KA, Torday JS, Sunday ME. Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4357-61. PMID: 7753811.

Masui A, Kato N, Itoshima T, et al. Scratching behavior induced by bombesin-related peptides. Comparison of bombesin, gastrin-releasing peptide and phyllolitorins. Eur J Pharmacol. 1993 Jul 20;238(2-3):297-301. PMID: 7691621.

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

Custom Order

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