| Product Unit Size | Cost | Quantity | Stock |
|---|
Procarbazine is a hydrazine derivative that exhibits anticancer chemotherapeutic activity. Procarbazine acts as a DNA alkylator and induces double stranded DNA breaks and causes oxidative damage. Clinically, procarbazine is used to treat Hodgkin’s lymphoma and brain cancers. This compound also inhibits monoamine oxidase (MAO).
| Cas No. | 366-70-1 |
|---|---|
| Purity | ≥97% |
| Formula | C12H19N3O • HCl |
| Formula Wt. | 257.76 |
| Chemical Name | N-(1-Methylethyl)-4-[(2- methylhydrazino)methyl]- benzamide hydrochloride |
| IUPAC Name | 4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;hydrochloride |
| Synonym | Matulane, Natulan |
| Melting Point | 223-226°C |
| Solubility | Soluble in water. |
| Appearance | White crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Ogawa K, Hiraku Y, Oikawa S, et al. Molecular mechanisms of DNA damage induced by procarbazine in the presence of Cu(II). Mutat Res. 2003 Aug 5;539(1-2):145-55. PMID: 12948823.
Kyrtopoulos SA, Anderson LM, Chhabra SK, et al. DNA adducts and the mechanism of carcinogenesis and cytotoxicity of methylating agents of environmental and clinical significance. Cancer Detect Prev. 1997;21(5):391-405. PMID: 9307842.