LKT Labs

Biochemicals for Life Science Research

Procaterol Hydrochloride

Product ID P7056
Cas No. 62929-91-3
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $106.40 In stock
10 mg $191.70 In stock
25 mg $429.50 In stock
100 mg $1,229.90 In stock
Bulk Quote

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Description

Procaterol is an agonist at β2-adrenergic receptors that exhibits anti-inflammatory, anti-asthma, and bronchodilatory activities. Procaterol is used to treat asthma. In animal models, procaterol suppresses anaphylactic reactions. In bronchial epithelial cells, procaterol inhibits release of RANTES, GM-CSF, and IL-8, inhibiting eosinophil chemotaxis. Additionally, procaterol decreases expression of intracellular adhesion molecule 1 (ICAM-1) and vascular cellular adhesion molecule 1 (VCAM-1), inhibiting adhesion of eosinophils to fibroblasts.

Product Info

Cas No.

62929-91-3
Purity

≥98%
Formula

C16H22N2O3 • HCl
Formula Wt.

326.82
IUPAC Name

8-hydroxy-5-[(1R, 2S)-1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one;hydrochloride
Synonym

Meptin, Lontermin
Melting Point

213-215C
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

P7056 MSDS PDF
Info Sheet

P7056 Info Sheet PDF

References

Bao W, Chen Q, Lin Y, et al. Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma. Respirology. 2013 Nov;18 Suppl 3:53-61. PMID: 24188204.

Yoshida N, Muraguchi M, Kamata M, et al. Procaterol potentiates the anti-inflammatory activity of budesonide on eosinophil adhesion to lung fibroblasts. Int Arch Allergy Immunol. 2009;150(4):352-8. PMID: 19571567.

Koyama S, Sato E, Masubuchi T, et al. Procaterol inhibits IL-1beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity. Eur Respir J. 1999 Oct;14(4):767-75. PMID: 10573218.

Ohuchi K, Hirasawa N, Takeda H, et al. Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats. Int Arch Allergy Appl Immunol. 1987;82(1):26-32. PMID: 2879797.

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