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Propranolol Hydrochloride

Propranolol Hydrochloride

Product ID P6865
Cas No. 318-98-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $48.50 In stock
5 g $71.70 In stock
25 g $148.90 In stock
100 g $358.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Propanolol hydrochloride is a nonselective β1/2-adrenergic receptor antagonist that exhibits anti-arrhythmic and antihypertensive properties. Propanolol is most often used to decrease blood pressure and heart rate. Additionally, the β-adrenergic receptor blockade modulates catecholamine levels and increases protein synthesis, resulting in the ability of propranolol to attenuate wound healing-induced hypermetabolic responses during burn treatment. Propanolol also displays benefit as an anti-migraine prophylactic, inhibiting the cortical spreading during depression that may be responsible for migraines.

Product Info

Cas No.

318-98-9

Purity

≥98%

Formula

C16H21NO2 • HCl

Formula Wt.

295.80

IUPAC Name

1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P6865 MSDS PDF

Info Sheet

P6865 Info Sheet PDF

References

Ji Y, Li K, Xiao X, et al. Effects of propranolol on the proliferation and apoptosis of hemangioma-derived endothelial cells. J Pediatr Surg. 2012 Dec;47(12):2216-23. PMID: 23217879.

Izadpanah A, Izadpanah A, Kanevsky J, et al. Propranolol versus corticosteroids in the treatment of infantile hemangioma: a systematic review and meta-analysis. Plast Reconstr Surg. 2013 Mar;131(3):601-13. PMID: 23142941.

Romana-Souza B, Santos JS, Monte-Alto-Costa A. beta-1 and beta-2, but not alpha-1 and alpha-2, adrenoceptor blockade delays rat cutaneous wound healing. Wound Repair Regen. 2009 Mar-Apr;17(2):230-9. PMID: 19320892.

Casucci G, Villani V, Frediani F. Central mechanism of action of antimigraine prophylactic drugs. Neurol Sci. 2008 May;29 Suppl 1:S123-6. PMID: 18545912.

Pereira CT, Jeschke MG, Herndon DN. Beta-blockade in burns. Novartis Found Symp. 2007;280:238-48. PMID: 17380798.

Garvey HL, Ram N. Comparative antihypertensive effects and tissue distribution of beta adrenergic blocking drugs. J Pharmacol Exp Ther. 1975 Jul;194(1):220-33. PMID: 1151751.

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