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Proteolipid Protein (139-151)

Proteolipid Protein (139-151)

Product ID P4560
Cas No. 122018-58-0
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $245.30 In stock
5 mg $940.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Proteolipid protein (PLP, 139-151) is the immunodominant peptide fragment of PLP. This peptide is endogenously expressed in the central nervous system and is commonly used to induce experimental autoimmune encephalitis (EAE), an autoimmune disease similar to multiple sclerosis, in animal models.

Product Info

Cas No.

122018-58-0

Purity

≥95%

Formula

C72H104N20O17

Formula Wt.

1521.7

Synonym

PLP

Solubility

Soluble in water (2 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P4560 MSDS PDF

Info Sheet

P4560 Info Sheet PDF

References

Soellner IA, Rabe J, Mauri V, et al. Differential aspects of immune cell infiltration and neurodegeneration in acute and relapse experimental autoimmune encephalomyelitis. Clin Immunol. 2013 Dec;149(3):519-29. PMID: 24239839.

Nicolò C, Sali M, Di Sante G, et al. Mycobacterium smegmatis expressing a chimeric protein MPT64-proteolipid protein (PLP) 139-151 reorganizes the PLP-specific T cell repertoire favoring a CD8-mediated response and induces a relapsing experimental autoimmune encephalomyelitis. J Immunol. 2010 Jan 1;184(1):222-35. PMID: 19949067.

Custom Order

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