Puerarin, High Purity

Name: Puerarin, High Purity
SKU: P8117
Availability: InStock

Product ID P8117

Cas No. 3681-99-0

Purity ≥99%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Puerarin is an isoflavone derivative of daidzein found in Pueraria (Radix); it exhibits anxiolytic, cardioprotective, neuroprotective, and antioxidative activities. This compound also acts as a phytoestrogen. Puerarin acts as an antagonist at 5-HT2C receptors and at the benzodiazepine site on GABA-A receptors. Puerarin increases social interaction time and locomotor activity in animal models of substance withdrawal and inhibits cognitive impairment in the Morris water maze paradigm in animal models of Alzheimer’s disease. Additionally, puerarin decreases systolic blood pressure and heart rate and downregulates expression of P2X3 receptors in animal models of myocardial ischemia/reperfusion. This compound also protects neurons against H2O2-induced oxidative stress in vitro.

Product Info

Cas No.	3681-99-0
Purity	≥99%
Formula	C₂₁H₂₀O₉
Formula Wt.	416.38
Chemical Name	8-β-D-glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-(9CI)4H-1-Benzopyran-4-one
IUPAC Name	7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Melting Point	187°C
Solubility	Soluble in methanol. Slightly soluble in ethanol.
Appearance	White powder with yellow cast

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	P8117 MSDS PDF
Info Sheet	P8117 Info Sheet PDF

References

Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

Malaivijitnond S, Tingmunnuthum D, Gittarasanee S, et al. Puerarin exhibits weak estrogenic activity in female rats. Fitoterapia. 2010 Sep;81(6):569-576. PMID: 20117180.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Phone
This field is for validation purposes and should be left unchanged.

Puerarin, High Purity

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Etidronate Disodium

Virginiamycin Mixture

Bafilomycin A1

Rosmarinic Acid

Lactacystin

Melatonin

GS-9901

Rivastigmine Tartrate

Paclitaxel, from Taxus yunnanensis

Boc-FLFLF

Remdesivir

Tanshinone I

Ketoconazole

Paroxetine Hydrochloride Hemihydrate

Diosgenin

Trimetazidine Dihydrochloride

5-Fluorouracil

Artesunate

Ornidazole

Oxymetazoline Hydrochloride

Footer