Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that non-selectively inhibits COX-1 and COX-2. Ibuprofen exhibits anti-inflammatory, antipyretic, analgesic, and neuroprotective activities. This compound shows protective efficacy against Alzheimer’s disease when administered clinically.
Ibuprofen is supplied as a crystalline solid. A stock solution may be made by dissolving the Ibuprofen in an organic solvent purged with an inert gas. Ibuprofen is soluble in solvents such as DMSO, ethanol, and dimethyl formamide. The solubility of Ibuprofen in these solvents is approximately 45 mg/ml. If the Ibuprofen needs to be stored long term, we recommend storing the solid Ibuprofen and not storing the Ibuprofen in solution due to potential loss of stability.