• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
S-Trityl-L-cysteine

S-Trityl-L-cysteine

Product ID T7232
Cas No. 2799-07-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $100.40 In stock
25 g $392.10 In stock
100 g $1,172.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

S-Trityl-L-cysteine (STLC) is an organosulfur compound found in garlic plants. STLC exhibits anticancer and potential chemotherapeutic activities across several models. STLC acts as a mitotic inhibitor, inhibiting mitotic kinesin Eg5 and preventing separation of duplicated chromosomes and formation of bipolar spindles during mitosis. In chronic myelogenous leukemia (CML) cells, STLC induces cleavage of poly(ADP)-ribose polymerase (PARP) and activation of caspase 3, resulting in apoptosis and cell death.

Product Info

Cas No.

2799-07-7

Purity

≥98%

Formula

C22H21NO2S

Formula Wt.

363.47

Chemical Name

S-(Triphenylmethyl)-L-cysteine

IUPAC Name

(2R)-2-amino-3-tritylsulfanylpropanoic acid

Synonym

NSC83265

Solubility

Soluble in water (partly), DMSO (5 mg/ml), and methanol

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T7232 MSDS PDF

Info Sheet

T7232 Info Sheet PDF

Brochures

Natural Products Flyer

References

Abualhasan MN, Good JA, Wittayanarakul K, et al. Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine. Eur J Med Chem. 2012 Aug;54:483-98. PMID: 22749640.

Shimizu M, Ishii H, Ogo N, et al. S-trityl-L-cysteine derivative induces caspase-independent cell death in K562 human chronic myeloid leukemia cell line. Cancer Lett. 2010 Dec 1;298(1):99-106. PMID: 20619960.

Kozielski F, Skoufias DA, Indorato RL, et al. Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5. Proteomics. 2008 Jan;8(2):289-300. PMID: 18186019.

Skoufias DA, DeBonis S, Saoudi Y, et al. S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. J Biol Chem. 2006 Jun 30;281(26):17559-69. PMID: 16507573.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M1845

    Melitracen Hydrochloride

    Tricyclic antidepressant; potential D1/2 antago...

    ≥99%
  • A528251

    Angiotensin I/II (1-7)(DP-7)

    Peptide fragment

    ≥95%
  • O7053

    L-Ornithine Hydrochloride

    Non-proteinogenic amino acid, L-arginine metabo...

    ≥98%
  • S824766

    Sutezolid

    Bactericidal.

    ≥98%
  • A2044

    Aflatoxin B1

    Mycotoxin produced by species of Aspergillus; D...

    ≥98%
  • B1992

    Bexarotene

    RXR agonist.

    ≥98%
  • S3584

    Sivelestat Sodium Tetrahydrate

    Neutrophil elastase inhibitor.

    ≥99%
  • D5794

    Doxorubicin Hydrochloride

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • E5216

    β-Endorphin, camel

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • H9711

    (Z)-4-Hydroxytamoxifen

    SERM.

    ≥98%
  • L1782

    Levodopa

    Endogenous catecholamine precursor, also found ...

    ≥98%
  • C022682

    2-Carbomethoxy-3-thiophenesulfonyl Chloride

    Building block

    ≥98%
  • L9609

    Lycopene

    Carotene pigment found in red and green fruits ...

    ≥90%
  • C4757

    Clozapine

    M4 mAChR agonist, 5-HT1A partial agonist, M1/2/...

    ≥97%
  • T0077

    Transactivator of Transcription Peptide (2-4)

    Peptide, contains two cell-penetrating sequence...

    ≥95%
  • A7460

    Asparaginase

    Catalyzes hydrolysis of asparagine.

    ≥98%
  • B3472

    4,4′-(1,1′-Biphenyl-4,4′-diyldioxy)dianiline

    Potential VEGFR2, Met, RET, Axl, Ron, PDGFR, FG...

    ≥98%
  • A5133

    Amiloride Hydrochloride Dihydrate

    K+-sparing diuretic; ENaC and acid-sensing ion ...

    ≥98%
  • R2788

    RGW-611

    Morpholine derivative.

    ≥98%
  • R3205

    Ribavirin

    Purine nucleoside analog; DNA chain terminator....

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only