• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
R-(+)-Ofloxacin

R-(+)-Ofloxacin

Product ID O2146
Cas No. 100986-86-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $225.90 In stock
5 mg $989.50 In stock
10 mg $1,735.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

R-(+)-Ofloxacin is the optically active isomer of ofloxacin, a second generation fluoroquinolone antibiotic. This compound is often given as a topical treatment for ocular and otic infections. Like other fluoroquinolones, ofloxacin inhibits DNA gyrase and topoisomerase IV; it exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Under UV light, ofloxacin exhibits phototoxicity, disrupting the mitochondrial membrane potential and inducing ROS-mediated DNA damage.

Product Info

Cas No.

100986-86-5

Purity

≥98%

Formula

C18H20FN3O4

Formula Wt.

361.37

Chemical Name

(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benz- oxazine-6-carboxylic acid

IUPAC Name

(2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Melting Point

225-227°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

O2146 MSDS PDF

Info Sheet

O2146 Info Sheet PDF

References

Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S3476

    Sitagliptin Phosphate Monohydrate

    DPP4 inhibitor.

    ≥98%
  • C0145

    Calcitriol

    Active form of vitamin D, regulates dietary Ca2...

    ≥97%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • G0106

    Gabapentin

    GABA analog; GABA potentiator, adenosine A1 ago...

    ≥98%
  • O4672

    Olsalazine Sodium

    5-Aminosalicylate prodrug, NSAID; COX-1/2 inhib...

    ≥98%
  • B3300

    BI-6727

    PLK1 inhibitor.

    ≥99%
  • R0212

    Radicicol

    Benzoquinone ansamycin; topoisomerase VI-B, HSP...

    ≥96%
  • C0266

    Capsaicin, natural

    Found in Capsicum; TRPV agonist.

    ≥95%, capsaicinoids content
  • O9396

    Oxytetracycline

    Tetracycline; protein translation inhibitor.

    ≥96%
  • A1616

    AEE-788

    Inhibitor of EGFR, HER2, VEGFR2, and FLT3.

    ≥98%
  • C324091

    Ciclesonide

    Corticosteroid

    ≥98%
  • L960010

    LY-3200882

    TGF-β1 inhibitor.

    ≥98%
  • K0038

    Kahweol Oleate

    Diterpene found in coffee beans.

    ≥98%
  • C0147

    Calcium Folinate Pentahydrate

    Folate source co-administered with methotrexate...

    ≥95%
  • T2800

    Thalidomide

    Immunomodulator; teratogen.

    ≥98%
  • C0153

    Calcitonin, rat

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • T7135

    Triticonazole

    Triazole; 14-α demethylase inhibitor, potentia...

    ≥95%
  • O1179

    n-Octyl-4-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • N3452

    Nimustine Hydrochloride

    Nitrosourea, DNA cross-linker.

    ≥97%
  • A7204

    AS-605240

    p110δ PI3K inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only