• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
R-(+)-Ofloxacin

R-(+)-Ofloxacin

Product ID O2146
Cas No. 100986-86-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $225.90 In stock
5 mg $989.50 In stock
10 mg $1,735.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

R-(+)-Ofloxacin is the optically active isomer of ofloxacin, a second generation fluoroquinolone antibiotic. This compound is often given as a topical treatment for ocular and otic infections. Like other fluoroquinolones, ofloxacin inhibits DNA gyrase and topoisomerase IV; it exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Under UV light, ofloxacin exhibits phototoxicity, disrupting the mitochondrial membrane potential and inducing ROS-mediated DNA damage.

Product Info

Cas No.

100986-86-5

Purity

≥98%

Formula

C18H20FN3O4

Formula Wt.

361.37

Chemical Name

(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benz- oxazine-6-carboxylic acid

IUPAC Name

(2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Melting Point

225-227°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

O2146 MSDS PDF

Info Sheet

O2146 Info Sheet PDF

References

Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B1653

    Benzyl Isothiocyanate

    ITC found in cruciferous vegetables.

    ≥99%
  • P6802

    Pranoprofen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • N0068

    Naringenin

    Flavanone found in species of Citrus. Naringen...

    ≥98%
  • C3262

    Ciprofloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • E4418

    β-Elemene

    Sesquiterpene found in various plant sources. <...

    ≥98%
  • A4534

    Aliskiren Hemifumarate

    Renin inhibitor.

    ≥98%
  • D324090

    Diclofenac Impurity C

    Impurity of diclofenac

    ≥98%
  • F8151

    Fumonisin B3

    Mycotoxin produced by Fusarium fungi that infec...

    ≥98%
  • C9609

    Cyclophosphamide Monohydrate

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • U6857

    Urodilatin CCC

    ANP fragment, natriuretic peptide; Na+/K+ ATPas...

    ≥98%
  • F8150

    Fumonisin B2

    Mycotoxin produced by Fusarium; sphingosine acy...

    ≥97%
  • N0123

    Naftopidil

    α1-adrenergic antagonist.

    ≥98%
  • P9767

    Pyriproxyfen

    Juvenile insect hormone mimic.

    ≥95%
  • T3200

    Ticagrelor

    Nucleoside (adenosine) analog; P2Y12 antagonist...

    ≥98%
  • C4517

    Clenbuterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • C4533

    Clindamycin Phosphate

    Lincosamide; ribosomal translocation and protei...

    ≥98%
  • P1765

    Peptide Standard 1

    For use in amino acid analysis.

    ≥95%
  • A6264

    Apramycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • T8006

    Tubastatin A Hydrochloride

    HDAC6/10 inhibitor.

    ≥98%
  • A9978

    Aztreonam

    β-lactam; penicillin binding protein inhibitor...

    ≥96%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only