• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Radicicol

Radicicol

Product ID R0212
Cas No. 12772-57-5
Purity ≥96%
Product Unit SizeCostQuantityStock
1 mg $132.60 In stock
5 mg $571.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Radicicol is an analog of benzoquinone ansamycin that inhibits HSP90, Src family kinases, and Raf. Radicicol exhibits neuroprotective, antibiotic, antifungal, anti-parasitic, and antimalarial activities. In Plasmodium, radicicol targets topoisomerase VI-B, inhibiting mitochondrial replication. Radicicol also increases survival and neurite outgrowth of neurons in chick embryos.

Product Info

Cas No.

12772-57-5

Purity

≥96%

Formula

C18H17ClO6

Formula Wt.

364.78

Chemical Name

8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihyroxy-14- methyl-6H-oxireno[e][2]benzoxacyclotetradecin- 6,12(7H)-dione

IUPAC Name

(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione

Synonym

Monorden, Monorderne

Melting Point

193.5°C

Solubility

Soluble in DMSO, methanol or ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

R0212 MSDS PDF

Info Sheet

R0212 Info Sheet PDF

References

Chalapareddy S, Bhattacharyya MK, Mishra S, et al. Radicicol Confers Mid-Schizont Arrest by Inhibiting Mitochondrial Replication in Plasmodium falciparum. Antimicrob Agents Chemother. 2014 Aug;58(8):4341-4352. PMID: 24841259.

Gadelle D, Bocs C, Graille M, et al. Inhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicol. Nucleic Acids Res. 2005 Apr 22;33(7):2310-7. PMID: 15849317.

Sano M, Yoshida M, Fukui S, et al. Radicicol potentiates neurotrophin-mediated neurite outgrowth and survival of cultured sensory neurons from chick embryo. J Neurochem. 1999 Jun;72(6):2256-63. PMID: 10349833.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P0346

    Palosuran Hydrochloride

    Urotensin II receptor antagonist.
  • H1648

    Hemorphin-7

    Endogenous opioid peptide derived from the β-c...

    ≥95%
  • F4502

    Flavokawain A

    Chalcone kavalactone found in Piper methysticum...

    ≥98%
  • M1613

    Medroxyprogesterone 17-Acetate

    Synthetic steroid used in HRT; PR, AR, glucocor...

    ≥99%
  • A0966

    Adrenocorticotropic Hormone (1-16), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • M568268

    Mogroside IV

    Triterpenoid

    ≥98%
  • T5870

    Torin 1

    Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...

    ≥98%
  • T0096

    Cephalomannine

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • P3463

    Piperacillin Sodium

    β-lactam; penicillin binding protein inhibitor...

    ≥95%
  • A1368

    Adrenomedullin (1-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • C0374

    β-Casomorphin, human

    Peptide, casein fragment.

    ≥95%
  • B7973

    Busulfan

    Alkyl sulfonate; DNA alkylator.

    ≥98%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%
  • E5576

    Entecavir

    Nucleoside (deoxyguanosine) analog; DNA chain t...

    ≥97%
  • G4400

    Glabridin

    Isoflavonoid found in Glycyrrhiza; GABA-A posit...

    ≥98%
  • G7443

    GSK-429286A

    ROCK1/2 inhibitor, potential RSK and p70S6K inh...

    ≥98%
  • L3551

    Limonin Glucoside

    Furanolactone found in Citrus.

    ≥95%
  • C1718

    Cepharanthine, 95%

    Alkaloid found in Stephania.

    ≥95%
  • Q8019

    Quetiapine Fumarate

    5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...

    ≥99%
  • R1985

    Reveromycin A

    Isoleucyl-tRNA synthase inhibitor, osteoclast p...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only