• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Scriptaid

Scriptaid

Product ID S1069
Cas No. 287383-59-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $152.70 In stock
5 mg $587.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Scriptaid is an inhibitor of histone deacetylases that exhibits anticancer activity. In non-small cell lung cancer (NSCLC) cells, scriptaid downregulates expression of Chk1. In glioma cells, scriptaid increases activation of JNK and p38 MAPK, expression of p21 and p27, and activity of Ras; it also decreases activity of telomerase, inducing apoptosis and decreasing proliferation. In somatic cell nuclear transfer, scriptaid improves the quality of cloned mouse embryos.

Product Info

Cas No.

287383-59-9

Purity

≥98%

Formula

C18H18N2O4

Formula Wt.

326.35

Chemical Name

6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)- hexanoic acid hydroxyamide

IUPAC Name

6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide

Synonym

CGK1026, Scriptide

Solubility

Soluble in DMSO (1mg/mL) or methanol.

Appearance

Off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

S1069 MSDS PDF

Info Sheet

S1069 Info Sheet PDF

References

Bui HT, Seo HJ, Park MR, et al. Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. Biol Reprod. 2011 Nov;85(5):1048-56. PMID: 21753193.

Brazelle W, Kreahling JM, Gemmer J, et al. Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells. PLoS One. 2010 Dec 14;5(12):e14335. PMID: 21179472.

Sharma V, Koul N, Joseph C, et al. HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity. J Cell Mol Med. 2010 Aug;14(8):2151-61. PMID: 19583803.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • X0254

    Xanthohumol

    Prenylated flavonoid found in Humulus lupulus.<...

    ≥98%
  • P200637

    PF-04745637

    TRPA1 antagonist

    ≥98%
  • P200099

    PF-06939999

    PRMT5 inhibitor

    ≥98%
  • A5056

    Amorolfine Hydrochloride

    14α-demethylase inhibitor.

    ≥98.5%
  • C0278

    (+)-Catechin

    Flavanol originally found in Camilla (green tea...

    ≥99%
  • C4402

    Cladribine

    Nucleoside (deoxyadenosine) analog; DNA chain t...

    ≥98%
  • C1718

    Cepharanthine, 95%

    Alkaloid found in Stephania.

    ≥95%
  • D1748

    Demeclocycline Hydrochloride

    Tetracycline; protein translation inhibitor, po...

    ≥85%
  • P1770

    Perillyl Alcohol

    Terpene found in various plant and fruit source...

    ≥85%
  • A464768

    Altertoxin 1

    Mycotoxin contaminant in food and feed.

    ≥97%
  • C5618

    Coelenterazine, natural

    Light-emitting luciferin analog found in aquati...

    ≥98%
  • A5160

    Ampicillin Trihydrate

    β-lactam; transpeptidase inhibitor.

    ≥97%
  • R3197

    Rhynchophylline

    Oxyindole alkaloid found in Uncaria sinensis; h...

    ≥98%
  • H9812

    5-Hydroxytryptophol

    Serotonin/melatonin analog found in various pla...

    ≥98%
  • T0104

    Taxol Side Chain Methyl Ester

    Side chain attached to various taxanes.

    ≥96%
  • B0396

    BAY80-6946

    p110α PI3K inhibitor.

    ≥98%
  • U6860

    Urocortin III, mouse

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • S336486

    Simeprevir

    NS3/4A inhibitor

    ≥99%
  • R1985

    Reveromycin A

    Isoleucyl-tRNA synthase inhibitor, osteoclast p...

    ≥98%
  • E2258

    Efonidipine Hydrochloride

    Calcium channel blocker.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only