• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Somatostatin-14

Somatostatin-14

Product ID S5749
Cas No. 38916-34-6
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $551.60 In stock
10 mg $919.40 In stock
25 mg $1,838.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities. In vivo, somatostatin improves performance in the light/dark avoidance test. Somatostatin also suppresses seizures and prevents the generation of seizures, potentially through modulation of GABA signaling. Somatostatin induces cell death under hypoxic/ischemic conditions. In tumor cells, somatostatin displays pro-apoptotic properties, potentially involving the inhibition of PI3K/Akt signaling. Somatostatin also limits food intake and inhibits secretion of insulin and glucagon through alteration of Gβγ signaling and P/Q-type, N-type, and L-type voltage-gated Ca2+ channel signaling.

Product Info

Cas No.

38916-34-6

Purity

≥95%

Formula

C76H104N18O19S2

Formula Wt.

1637.92

Synonym

Somatostatin, Growth hormone release-inhibiting factor, Somatotropin release-inhibiting hormone

Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S5749 MSDS PDF

Info Sheet

S5749 Info Sheet PDF

References

Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E7329

    Ethoxyquin

    Quinoline, food preservative; HSP90 inhibitor.<...

    ≥90%
  • A1096

    Acyclovir

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • G3457

    Ginsenoside Re

    Triterpene saponin found in species of Panax; P...

    ≥98%
  • F3208

    Fibrinopeptide B, human

    Antimicrobial peptide, generated during fibrin ...

    ≥95%
  • T6932

    Triflumizole

    Imidazole; PPARγ agonist, RORγ inverse agonis...

    ≥95%
  • M4455

    MLN-2238

    Proteasome inhibitor, miR33b modulator.

    ≥95%
  • U5233

    Universal Tetanus Toxin Epitope P2 (830-844)

    Peptide, tetanus toxin epitope.

    ≥95%
  • G0152

    Ganciclovir

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • R0351

    Ramoplanin

    Peptide; peptidoglycan inhibitor.

    ≥90%
  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • T1656

    Tenoxicam Impurity B

    Tenoxicam impurity

    ≥98%
  • H978583

    Hyoscyamine sulfate dihydrate

    Tropane alkaloid found in plants in the Solanac...

    ≥99%
  • I5212

    Indirubin

    Bisindole isomer of indigo found in Indigo natu...

    ≥98%
  • K0031

    Kahweol Acetate

    Diterpene found in coffee beans.

    ≥98%
  • P1753

    Penicillamine

    Penicillin derivative, chelating agent; carboxy...

    ≥97%
  • T1878

    Tetrodotoxin Citrate

    Neurotoxin found in puffer fish; site 1 voltage...

    ≥99%
  • H9662

    Hypocrellin B

    Induces DNA strand breakage.

    ≥98%
  • A985120

    AZD-0156

    Inhibitor of ATM.

    ≥98%
  • L4796

    LY-294002

    PI3K inhibitor.

    ≥99%
  • C3260

    Ciprofibrate

    Fibrate; PPARα agonist.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only