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Stresscopin-Related Peptide, human

Stresscopin-Related Peptide, human

Product ID S7872
Cas No. 348626-74-4
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $183.80 In stock
1 mg $341.30 In stock
2.5 mg $603.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Stresscopin-related peptide is a 5-amino acid extension of urocortin II that includes a preceding H-P-G-S-R tag. Like urocortin II, stresscopin-related peptide is a member of the corticotropin-releasing factor (CRF) family that binds to the CRF type 2 receptor (CRFR2). Stresscopin-related peptide signaling results in suppression of food intake, delay of gastric emptying, hypotension/hypertension (depending on the model), and tachycardia. Stresscopin-related peptide and its analog urocortin II modulate stress responses and exhibits anorexigenic, anxiogenic, anxiolytic, and generally positive inotropic effects (such as increases in coronary blood blow and cardiac output) across a wide variety of in vivo models.

Product Info

Cas No.

348626-74-4

Purity

≥95%

Formula

C205H358N68O57

Formula Wt.

4687.56

Synonym

SRP

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S7872 MSDS PDF

Info Sheet

S7872 Info Sheet PDF

References

Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

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