• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Tamoxifen Citrate

Tamoxifen Citrate

Product ID T0250
Cas No. 54965-24-1
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $71.50 In stock
1 g $142.90 In stock
5 g $375.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tamoxifen is a selective estrogen receptor modulator (SERM) that acts as an ER agonist in the endometrium and as an ER antagonist in breast tissue; it also inhibits PKC. Tamoxifen exhibits anticancer chemotherapeutic, anti-angiogenic, anti-osteoporotic, and antipsychotic activities. Tamoxifen is also a prodrug, transformed into the active metabolite 4-hydroxytamoxifen in vivo. Tamoxifen shows some benefit in clinical settings in the treatment of bipolar I disorder and other mood disorders. In animal models, tamoxifen decreases blood vessel formation and inhibits angiogenesis. In osteoclasts, this compound induces apoptosis by increasing expression of FasL. Additionally, tamoxifen acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

Product Info

Cas No.

54965-24-1

Purity

≥98%

Formula

C26H29NO • C6H8O7

Formula Wt.

563.64

Chemical Name

(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N- dimethylethylamine citrate

IUPAC Name

2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N, N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid InChI: InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14- 22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13, 5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11, 12)/b26-25-;

Synonym

Kessar, Nolvadex, Taxus, Zynoplex, Zemide

Melting Point

143-146°C

Solubility

Slightly soluble in water. Soluble in ethanol, methanol or acetone.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T0250 MSDS PDF

Info Sheet

T0250 Info Sheet PDF

References

Yildiz A, Guleryuz S, Ankerst DP, et al. Protein kinase C inhibition in the treatment of mania: a double-blind, placebo-controlled trial of tamoxifen. Arch Gen Psychiatry. 2008 Mar;65(3):255-63. PMID: 18316672.

Krum SA, Miranda-Carboni GA, Hauschka PV, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J. 2008 Feb 6;27(3):535-45. PMID: 18219273.

Steiner AZ, Terplan M, Paulson RJ. Comparison of tamoxifen and clomiphene citrate for ovulation induction: a meta-analysis. Hum Reprod. 2005 Jun;20(6):1511-5. PMID: 15845599.

Blackwell KL, Haroon ZA, Shan S, et al. Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models. Clin Cancer Res. 2000 Nov;6(11):4359-64. PMID: 11106254.

Jordan VC. Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer. Br J Pharmacol. 1993 Oct;110(2):507-17. PMID: 8242225.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • J0240

    JAK2 Inhibitor V

    JAK2 inhibitor.

    ≥98%
  • O9256

    16-Oxocafestol

    Synthetic cafestol derivative.

    ≥97%
  • T2402

    TG100-115

    p110δ and p110γ PI3K inhibitor.

    ≥98%
  • R3014

    Recombinant TpN 47 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • L5993

    Loxoprofen Sodium Dihydrate

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • M2408

    MGCD-265 Analog

    MET inhibitor.

    ≥98%
  • I7468

    Isradipine

    Calcium channel blocker.

    ≥98%
  • T5996

    Tozasertib

    AurK, FLT3, Abl inhibitor.

    ≥98%
  • C0369

    Cardiogenol C Hydrochloride

    Induces cardiomyogenic effects in pluripotent c...

    ≥98%
  • P3209

    Piceatannol

    Polyphenolic hydroxystilbene, resveratrol deri...

    ≥99%
  • A1217

    Adefovir

    Acyclic nucleotide (adenosine) analog; viral DN...

    ≥98%
  • G3359

    Ginkgolide J

    Terpene lactone found in Ginkgo.

    ≥98%
  • G1308

    GDC-0032

    PI3K inhibitor.

    ≥98%
  • D1768

    Dermaseptin I

    Cationic antimicrobial peptide, alters bacteria...

    ≥96%
  • O938567

    4-epi-6-Oxodocetaxel

    Docetaxel impurity

    ≥95%
  • T0110

    Taxane Standard Mixture

    Mixture of taxanes.

    ≥98%
  • L1881

    Leuprolide Acetate

    GnRH analog; GnRH1 agonist.

    ≥95%
  • N3378

    S-Nitrosoglutathione

    NO donor.

    ≥95%
  • S0168

    Saracatinib

    Src and Abl inhibitor.

    ≥98%
  • P4008

    PKC412

    Staurosporine derivative; PKC and FLT3 inhibito...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only