Teicoplanin

Name: Teicoplanin
SKU: T1733
Availability: InStock

Product ID T1733

Cas No. 61036-62-2

Purity ≥900 ug/mg, bio assay

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Description

Teicoplanin is a glycopeptide antibiotic that displays antibacterial efficacy against gram positive bacteria. Teicoplanin is an analog of vancomycin with improved lipophilicity and bioavailability when given intramuscularly. Teicoplanin inhibits peptidoglycan formation and cell wall synthesis. This compound may also cause epileptogenic activity, potentially related to downstream modulation of GABA signaling. Teicoplanin is also used as a chiral selector in capillary liquid chromatography.

Product Info

Cas No.	61036-62-2
Purity	≥900 ug/mg, bio assay
Formula	C₈₈H₉₅Cl₂N₉O₃₃
Formula Wt.	1877.64
Chemical Name	Ristomycin A 34-O-[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(8-methyl-1-oxononyl)amino]-.beta.-D-glucopyranosyl]-42-O-.alpha.-D-mannopyranosyl-
Solubility	Soluble in water (10 mg/mL), ethanol, methanol, DMSO, DMF.
Appearance	White to light yellow powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	T1733 MSDS PDF
Info Sheet	T1733 Info Sheet PDF

References

Nailor MD, Sobel JD. Antibiotics for gram-positive bacterial infections: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, dalbavancin, and telavancin. Infect Dis Clin North Am. 2009 Dec;23(4):965-82, ix. PMID: 19909893.

Takechi K, Ishikawa T, Kamei C. Epileptogenic activity induced by teicoplanin and effects of some antiepileptics in mice. J Pharmacol Sci. 2008 Aug;107(4):428-33. PMID: 18678985.

Kafková B, Bosáková Z, Tesarová E, et al. Chiral separation of beta-adrenergic antagonists, profen non-steroidal anti-inflammatory drugs and chlorophenoxypropionic acid herbicides using teicoplanin as the chiral selector in capillary liquid chromatography. J Chromatogr A. 2005 Sep 23;1088(1-2):82-93. PMID: 16130735.

Somma S, Gastaldo L, Corti A. Teicoplanin, a new antibiotic from Actinoplanes teichomyceticus nov. sp. Antimicrob Agents Chemother. 1984 Dec;26(6):917-23. PMID: 6240963.

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Teicoplanin

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