• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Telmisartan

Telmisartan

Product ID T1644
Cas No. 144701-48-4
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $142.90 In stock
100 mg $245.30 In stock
500 mg $714.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Telmisartan is a long-acting antagonist at angiotensin II type 1 (AT II) receptors that is clinically used to treat hypertension. Telmisartan exhibits antihypertensive, anti-diabetic, anti-obesity, anti-inflammatory, and anti-hyperlipidemic activities. Telmisartan decreases levels of total cholesterol and LDL in vivo. Telmisartan also decreases weight gain and increases activity endurance and oxygen consumption in other animal models. This compound is also a selective modulator of PPARγ/δ, decreasing insulin, glucose, and triglyceride levels in high fat diet-fed rats. In endothelial cells, telmisartan decreases expression of MCP-1 and VCAM-1 and prevents activation of NF-κB.

Product Info

Cas No.

144701-48-4

Purity

≥98%

Formula

C33H30N4O2

Formula Wt.

514.63

Chemical Name

4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid

IUPAC Name

2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl] methyl]phenyl]benzoic acid

Synonym

BIBR 277, Micardis, Pritor

Melting Point

261-263°C

Solubility

Soluble in DMSO (1.2mg/mL). Insoluble in water. Chloroform.

Appearance

White to Off-White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T1644 MSDS PDF

Info Sheet

T1644 Info Sheet PDF

References

Xu S, Song H, Huang M, et al. Telmisartan inhibits the proinflammatory effects of homocysteine on human endothelial cells through activation of the peroxisome proliferator-activated receptor-δ pathway. Int J Mol Med. 2014 Sep;34(3):828-34. PMID: 24994548.

Sueta D, Koibuchi N, Hasegawa Y, et al. Telmisartan Exerts Sustained Blood Pressure Control and Reduces Blood Pressure Variability in Metabolic Syndrome by Inhibiting Sympathetic Activity. Am J Hypertens. 2014 May 28. [Epub ahead of print]. PMID: 24871627.

Feng X, Luo Z, Ma L, et al. Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway. J Cell Mol Med. 2011 Jul;15(7):1572-81. PMID: 20477906.

Inoue T, Taguchi I, Abe S, et al. Inhibition of intestinal cholesterol absorption might explain cholesterol-lowering effect of telmisartan. J Clin Pharm Ther. 2011 Feb;36(1):103-10. PMID: 21198725.

Benson SC, Pershadsingh HA, Ho CI, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May;43(5):993-1002. PMID: 15007034.

Okada M, Kosaka N, Hoshino Y, et al. Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biol Pharm Bull. 2010;33(9):1517-1521. PMID: 20823567.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0367

    S-(−)-Carbidopa Monohydrate

    Hydrazine; L-amino acid decarboxylase inhibitor...

    ≥98%
  • G4400

    Glabridin

    Isoflavonoid found in Glycyrrhiza; GABA-A posit...

    ≥98%
  • L9874

    L-(+)-Lysine Monohydrate

    Non-endogenous essential amino acid found in me...

    ≥95%
  • W9602

    WY-14643

    A peroxisome proliferator-activated receptor ag...

    ≥98%
  • T5847

    Tolvaptan

    V2 antagonist.

    ≥99%
  • C5680

    Coumestrol

    Phytoestrogen found in various plant sources; E...

    ≥97%
  • C294458

    Chlorzoxazone

    Centrally acting muscle relaxant.

    ≥99%
  • B030966

    BAY 11-7082

    inhibits inflammatory signaling

    ≥98%
  • T5946

    Toltrazuril

    Coccidiostat; mitochondrial respiration inhibit...

    ≥98%
  • F5871

    N-formyl-Met-Leu-Phe-Lys

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • E6245

    Eplerenone

    Mineralocorticoid antagonist.

    ≥99%
  • D3208

    Diclazuril

    Coccidiostat, GAPDH inhibitor.

    ≥98%
  • T0153

    Tanshinone I

    Diterpene found in Salvia.

    ≥95%
  • D1869

    Deracoxib

    NSAID; COX-2 inhibitor.

    ≥99%
  • A8644

    AVL-292

    BTK inhibitor.

    ≥98%
  • P0253

    Panaxadiol

    Triterpene sapongenin found in species of Panax...

    ≥98%
  • A145823

    ADU-S100 sodium salt

    Synthetic cyclic dinucleotide agonist of STING....

    ≥99%
  • A0822

    N-Acetyl-S-(N-methylsulfinylbutylthiocarbamoyl)-L-cysteine

    Sulforaphane-cysteine conjugate.

    ≥98%
  • L0528

    LBH-589

    HDAC1/2/3/11 inhibitor.

    ≥98%
  • T1298

    TDZD-8

    GSK-3β inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only