Description
Thalidomide has previously been clinically used as a sedative but was found to induce birth defects in pregnant females. Recently, thalidomide exhibits anticancer chemotherapeutic potential in the treatment of multiple myeloma. Additionally, thalidomide displays anti-inflammatory and immunomodulatory activities, improving TNBS-induced colitis in animal models by increasing expression of IL-10 and decreasing expression of TNF-α and IL-1β.