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Uracil is an endogenous pyrimidine base found in RNA. Derivatives of uracil such as 5-fluorouracil exhibit anticancer chemotherapeutic activity. Other derivatives display antibacterial efficacy. Uracil is used in the synthesis of caffeine and plays a role in glucose metabolism.
| Cas No. | 66-22-8 |
|---|---|
| Purity | ≥98% |
| Formula | C4H4N2O2 |
| Formula Wt. | 112.09 |
| Chemical Name | 2,4(1H,3H)-Pyrimidinedione |
| IUPAC Name | 1H-pyrimidine-2,4-dione |
| Synonym | 2,4-Dihydroxypyrimidine, 2,4-Pyrimidinediol |
| Melting Point | 335°C |
| Solubility | Soluble in hot water. Insoluble in alcohol or ether. soluble in ammonia water and other alkalies (pH 9.5). |
| Appearance | White Crystal Powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Matyugina E, Khandazhinskaya A, Chernousova L, et al. The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. Bioorg Med Chem. 2012 Nov 15;20(22):6680-6. PMID: 23062712.
Parker JB, Stivers JT. Dynamics of uracil and 5-fluorouracil in DNA. Biochemistry. 2011 Feb 8;50(5):612-7. PMID: 21190322.