Description
Vatalanib is an inhibitor of VEGFR1/2/3. It decreases tumor growth in models of human glioma when administered with HET0016, a 20-HETE synthesis inhibitor.
Product Unit Size | Cost | Quantity | Stock |
---|
Vatalanib is an inhibitor of VEGFR1/2/3. It decreases tumor growth in models of human glioma when administered with HET0016, a 20-HETE synthesis inhibitor.
Cas No. | 212141-54-3 |
---|---|
Purity | ≥98% |
Formula | C20H15ClN4 |
Formula Wt. | 346.82 |
Chemical Name | Vatalanib |
IUPAC Name | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine |
Synonym | PTK-787, PTK 787, PTK787, ZK-222584, ZK 222584, ZK222584, CGP-797870, ZK232934 |
Solubility | Solubility in DMSO - ~100 mg/mL. |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Shankar A., Borin T., et al. Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma. Onco Target Ther. 9:1204-19 (2016). PMID: 27022280.
Non-depolarizing NMJ blocker; AChR antagonist.<...
BRD2/3/4 inhibitor.
GSK-3β inhibitor.
Smo inhibitor.
Trichothecene mycotoxin produced by Fusarium; p...
Carotene pigment found in red and green fruits ...
Abl (T315I) inhibitor.
STING antagonist
Triterpene aglycone found in Radix Astragali; t...
Broad-spectrum antibiotic
Benzisoxazole; 5-HT7 and NMDA agonist, D-amino ...
Adenosine A2A agonist.
Impurity of rapamycin
Endogenous peptide involved in vascular contrac...
Cannabinoid receptor 2 selective agonist.
Taxane found in Taxus; DNA polymerase inhibitor...
Aminopeptidase inhibitor.
Endogenous precursor to all steroid hormones; T...
Nucleoside (guanosine) analog; RT, guanylyl cyc...
Endogenous peptide, cleavage product of AT II; ...