Description
Vatalanib is an inhibitor of VEGFR1/2/3. It decreases tumor growth in models of human glioma when administered with HET0016, a 20-HETE synthesis inhibitor.
Product Unit Size | Cost | Quantity | Stock |
---|
Vatalanib is an inhibitor of VEGFR1/2/3. It decreases tumor growth in models of human glioma when administered with HET0016, a 20-HETE synthesis inhibitor.
Cas No. | 212141-54-3 |
---|---|
Purity | ≥98% |
Formula | C20H15ClN4 |
Formula Wt. | 346.82 |
Chemical Name | Vatalanib |
IUPAC Name | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine |
Synonym | PTK-787, PTK 787, PTK787, ZK-222584, ZK 222584, ZK222584, CGP-797870, ZK232934 |
Solubility | Solubility in DMSO - ~100 mg/mL. |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Shankar A., Borin T., et al. Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma. Onco Target Ther. 9:1204-19 (2016). PMID: 27022280.
ATR inhibitor.
Quinoid diterpene found in species of Salvia; S...
Endogenous neuropeptide hormone, lowers extrace...
Lck, Src, SIK inhibitor.
Found in parsley.
β-lactam; penicillin binding protein inhibitor...
Alkaloid produced by Streptomyces, precursor in...
CRM1/XPO1 inhibitor.
Endogenous sterol component of animal cell memb...
Peptide, HIV-1 RT A2.1 epitope.
Antimicrobial found in essential oils from plan...
Pyrimidine nucleoside (cytidine) analog; DNA ch...
Benzazepine derivative; D1 partial agonist, pot...
Valsartan impurity
Endogenous peptide hormone fragment, involved i...
Cannabinoid receptor 2 selective agonist.
Endogenous cardiomodulatory peptide; NPR-A agon...
Building block
Analog of rapamycin.
Non-endogenous essential vitamin (B9), found in...