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Ziprasidone

Ziprasidone

Product ID Z3463
Cas No. 146939-27-7
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $55.00 In stock
500 mg $127.00 In stock
1 g $203.00 In stock
5 g $817.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ziprasidone is an atypical antipsychotic that acts as an antagonist at D2 receptors and 5-HT1D receptors and as an agonist at 5-HT1A receptors; this binding profile allows it to exhibit antipsychotic, antidepressant, and anxiolytic benefits. Ziprasidone is clinically used to treat bipolar disorder, schizophrenia, and sleeplessness/insomnia in individuals with psychosis. In a clinical setting, ziprasidone improved latency to REM, duration of slow wave sleep, total sleep time, and sleep efficiency.

Product Info

Cas No.

146939-27-7

Purity

≥98%

Formula

C21H21ClN4OS

Formula Wt.

412.94

Chemical Name

2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1- piperazinyl)ethyl)-6-chloro-1,3-dihydro-

IUPAC Name

5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1, 3-dihydroindol-2-one

Synonym

Geodon, Zeldox, CP-88059

Melting Point

213-215°C

Appearance

Pale brown powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

Z3463 MSDS PDF

Info Sheet

Z3463 Info Sheet PDF

References

Takeuchi H, Suzuki T, Bies RR, et al. Estimated dopamine D2 receptor occupancy from plasma concentrations of atypical antipsychotics and subjective experience/drug attitude in schizophrenia: an analysis of the CATIE data. Schizophr Res. 2013 Nov;150(2-3):373-9. PMID: 24028745.

Findling RL, Cavuş I, Pappadopulos E, et al. Efficacy, long-term safety, and tolerability of ziprasidone in children and adolescents with bipolar disorder. J Child Adolesc Psychopharmacol. 2013 Oct;23(8):545-57. PMID: 24111980.

Baskaran A, Summers D, Willing SL, et al. Sleep architecture in ziprasidone-treated bipolar depression: a pilot study. Ther Adv Psychopharmacol. 2013 Jun;3(3):139-49. PMID: 24167686.

Farah A. Atypicality of atypical antipsychotics. Prim Care Companion J Clin Psychiatry. 2005;7(6):268-74. PMID: 16498489.

Stimmel GL, Gutierrez MA, Lee V. Ziprasidone: an atypical antipsychotic drug for the treatment of schizophrenia. Clin Ther. 2002 Jan;24(1):21-37. PMID: 11833834.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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