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Salbutamol is a short-acting agonist at β2-adrenergic receptors that is clinically used to treat asthma and chronic obstructive pulmonary disorder (COPD). Salbutamol exhibits bronchodilatory, anti-asthma, tocolytic, antioxidative, and anti-inflammatory activities. In vivo, salbutamol decreases carrageenan-induced inflammation and nociception, suppresses activity of myeloperoxidase, and increases activity of superoxide dismutase and levels of glutathione.
| Cas No. | 51022-70-9 |
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| Purity | ≥98% |
| Formula | (C13H21NO3)2 • H2SO4 |
| Formula Wt. | 576.70 |
| Chemical Name | α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol sulfate |
| IUPAC Name | 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;sulfuric acid |
| Synonym | Aerolin, Asmaven, Ecovent, Loftan, Salbumol, Salbuvent, Venetlin, Volmax, salbutamol hemisulfate, Albuterol sulfate |
| Melting Point | 180°C |
| Solubility | Soluble in water. Slightly soluble in ethanol. |
| Appearance | White-almost white crystalline powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.
Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.