LKT Labs

Biochemicals for Life Science Research

Ginsenoside F2

Ginsenoside F2

Product ID G3461
Cas No. 62025-49-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $152.70 In stock
5 mg $382.10 In stock
10 mg $668.60 In stock
Bulk Quote

Quicklinks

Description

Ginsenoside F2 is a triterpene saponin originally found in species of Panax that exhibits anti-obesity and anticancer chemotherapeutic activities. Ginsenoside F2 inhibits hair cell apoptosis, decreasing expression of TGF-β2, SCAP, and SREBP in vivo. Ginsenoside F2 also decreases lipid accumulation in adipocytes, suppressing expressing of PPARγ and perilipin and inhibiting adipogenesis. This compound also induces formation of acidic vesicles, autophagy, and mitochondrial apoptosis in breast cancer stem cells; additionally, it decreases tumor growth in animal models of glioblastoma.

Product Info

Cas No.

62025-49-4
Purity

≥98%
Formula

C42H72O13
Formula Wt.

785.03
IUPAC Name

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

G3461 MSDS PDF
Info Sheet

G3461 Info Sheet PDF

References

Shin HS, Park SY, Hwang ES, et al. Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model. Biol Pharm Bull. 2014;37(5):755-63. PMID: 24789999.

Siraj FM, Sathishkumar N, Kim YJ, et al. Ginsenoside F2 possesses anti-obesity activity via binding with PPARγ and inhibiting adipocyte differentiation in the 3T3-L1 cell line. J Enzyme Inhib Med Chem. 2014 Mar 25. [Epub ahead of print]. PMID: 24666293.

Mai TT, Moon J, Song Y, et al. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells. Cancer Lett. 2012 Aug 28;321(2):144-53. PMID: 22326284.

Quan LH, Piao JY, Min JW, et al. Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102. J Ginseng Res. 2011 Sep;35(3):344-51. PMID: 23717079.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N6272

    NPS-2143 Hydrochloride

    Ca2+-sensing receptor antagonist.

    ≥99%
  • B1992

    Bexarotene

    RXR agonist.

    ≥98%
  • A4438

    Allatostatin I

    Neuropeptide found in insects; juvenile hormone...

    ≥95%
  • I7074

    Irsogladine Maleate

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • D5747

    Dolasetron Mesylate Hydrate

    5-HT3 antagonist.

    ≥98%
  • E8657

    Evodiamine

    Indole alkaloid found in Evodia rutaecarpa; top...

    ≥98%
  • E6234

    Epigallocatechin Gallate

    Flavanol found in Camilla (green tea); AhR ant...

    ≥98%
  • T0108

    10-Deacetyl-7-xylosyltaxol

    Taxane found in species of Taxus; potential mic...

    ≥98%
  • A5033

    4-Aminosalicylic Acid

    Dihydrofolate reductase inhibitor.

    ≥98%
  • M0125

    Magnolol

    Lignan found in Magnolia; GABA-A potentiator.

    ≥98%
  • M2409

    MGCD-0103

    HDAC inhibitor.

    ≥98%
  • N5655

    Nonoxynol-9

    Nonoxynol surfactant.

    90-110%
  • A5161

    Ampiroxicam

    Piroxicam prodrug, NSAID; COX-1/2 inhibitor.

    ≥98%
  • P8169

    Purpurin

    Anthraquinone pigment found in madder root; O-a...

    ≥90%
  • M9368

    Myristicin

    Allylbenzene found in spices and umbelliferous ...

    ≥98%
  • E7857

    Etofenamate

    NSAID; COX-1/2 and lipoxygenase inhibitor.

    ≥98%
  • A4944

    Amlexanox

    Azoxanthone derivative; S100A12 and S100A13 inh...

    ≥99%
  • O938565

    6-Oxodocetaxel

    Docetaxel impurity

    ≥98%
  • I0518

    I-BET-762

    BRD inhibitor.

    ≥98%
  • R9632

    Recombinant Zika Virus NS1 Antigen

    Zika Virus antigen