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Flutriafol

Product ID F4883
Cas No. 76674-21-0
Purity ≥97%
Product Unit SizeCostQuantityStock
500 mg $101.80 In stock
5 g $254.50 In stock
25 g $651.80 In stock
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  • Product Info
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  • Description
  • Product Info
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Description

Flutriafol is a triazole antifungal pesticide; it acts as a demethylation inhibitor, preventing sterol biosynthesis and disrupting membrane function. Flutriafol may also exhibit neuromodulatory and antioxidative activity in vivo, as it induces release of dopamine in the rat striatum through overstimulation of NMDA receptors and increasing NO production. Flutriafol-evoked dopamine release also appears to be dependent on Na+ and Ca2+ signaling.

Product Info

Cas No.

76674-21-0

Purity

≥97%

Formula

C16H13F2N3O

Formula Wt.

301.29

Chemical Name

1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)ethanol

IUPAC Name

1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)ethanol

Synonym

Impact

Appearance

White to yellowish powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4883 MSDS PDF

Info Sheet

F4883 Info Sheet PDF

References

Faro LR, Alfonso M, Maués LA, et al. Role of ionotropic glutamatergic receptors and nitric oxide in the effects of flutriafol, a triazole fungicide, on the in vivo striatal dopamine release. J Toxicol Sci. 2012;37(6):1135-42. PMID: 23208429.

Santana MB, Rodrigues KJ, Durán R, et al. Evaluation of the effects and mechanisms of action of flutriafol, a triazole fungicide, on striatal dopamine release by using in vivo microdialysis in freely moving rats. Ecotoxicol Environ Saf. 2009 Jul;72(5):1565-71. PMID: 19232726.

Griffiths KM, Howlett BJ. Transcription of sterol Delta(5,6)-desaturase and sterol 14alpha-demethylase is induced in the plant pathogenic ascomycete, Leptosphaeria maculans, during treatment with a triazole fungicide. FEMS Microbiol Lett. 2002 Nov 19;217(1):81-7. PMID: 12445649.

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