Description
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
| Cas No. | 313553-47-8 |
|---|---|
| Purity | ≥98% |
| Formula | C18H16N2OS |
| Formula Wt. | 308.40 |
| Chemical Name | N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)benzamide |
| IUPAC Name | N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide |
| Synonym | Hec1/Nek2 Mitotic Pathway Inhibitor I; Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-; IBT13131; AC1LIOIV |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Guikai Wu, Xiao-Long Qiu, Longen Zhou, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008, 68(20): 8393–8399. PMID 18922912.
Tetracycline; protein translation inhibitor.
Macrolide antibiotic; peptidyl transferase inhi...
A fungal metabolite that inhibits protein synth...
Antimicrobial peptide found in bee and wasp ven...
p110α PI3K inhibitor.
Xanthine alkaloid found in coffee, tea, and oth...
Non-depolarizing NMJ blocker; nAChR antagonist....
Glutamine analog; γ-glutamyl transferase, CTP ...
Prenylated chalcone flavonoid found in Psoralea...
Found in Aristolochia and Radix; PLA2 inhibitor...
Steroid hormone involved in stress signaling; g...
Cembranoid found in Sarcophyton.
ITC, erucin analog.
COMT inhibitor.
Imidazole; 14-α demethylase inhibitor, potenti...
ATP-sensitive K+ channel activator, α-adrenerg...
Benzophenanthridine alkaloid; topoisomerase I i...
Non-nitrogen bisphosphonate; mitochondrial ATP/...
Regioisomers
5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...