Description
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
| Cas No. | 313553-47-8 |
|---|---|
| Purity | ≥98% |
| Formula | C18H16N2OS |
| Formula Wt. | 308.40 |
| Chemical Name | N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)benzamide |
| IUPAC Name | N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide |
| Synonym | Hec1/Nek2 Mitotic Pathway Inhibitor I; Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-; IBT13131; AC1LIOIV |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Guikai Wu, Xiao-Long Qiu, Longen Zhou, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008, 68(20): 8393–8399. PMID 18922912.
Third generation macrocyclic ALK inhibitor.
Inhibitor of EGFR/HER2 (ErbB2).
Sulfur analog of furan found in cooked meat pro...
p110β PI3K inhibitor.
nNOS inhibitor.
Naturally produced ITC, sulfonyl analog of sulf...
Tretraeptide, binds cell surface integrins.
Imidazole; 14-α demethylase inhibitor.
DNA alkylator.
Tripeptide, binds cell surface integrins.
Found in Paeonia, Arisaema, Dioscorea; MAO-A/B ...
GABA potentiator, voltage-gated Na+ and ATP-sen...
p110α PI3K inhibitor.
Endogenous quaternary ammonium, required for fa...
Synthetic steroid hormone, estrogen analog, use...
Flavonoid found in Rhus verniciflua and Butea m...
Vitamin A metabolite, differentiation inducer; ...
EGFR inhibitor.
Pyridine; PDE3 inhibitor.
β2-adrenergic agonist.