Description
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
INH1 is a small molecule found to disrupt the Hec1/Nek2 interaction via direct Hec1 binding, leading to apoptosis.
| Cas No. | 313553-47-8 |
|---|---|
| Purity | ≥98% |
| Formula | C18H16N2OS |
| Formula Wt. | 308.40 |
| Chemical Name | N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)benzamide |
| IUPAC Name | N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide |
| Synonym | Hec1/Nek2 Mitotic Pathway Inhibitor I; Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-; IBT13131; AC1LIOIV |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Guikai Wu, Xiao-Long Qiu, Longen Zhou, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008, 68(20): 8393–8399. PMID 18922912.
beta-Amyloid anti-oligomer and aggregation inhi...
Inhibitor of Abl, c-Kit, and PDGFR.
Flavonoid found in fruits, vegetables, and grai...
Saponin found in species of Panax; PPARγ agoni...
Indirect activator of STING signaling
Endogenous peptide hormone fragment, involved i...
Dienolide kavalactone originally found in Piper...
SIRT1/2 inhibitor, indirect p53 activator.
Pyridine; PDE3 inhibitor.
Serum response factor inhibitor and MRTF-A bind...
5-FU prodrug; thymidylate synthase inhibitor.
Endogenous calcitonin-family peptide frgament, ...
V2 antagonist.
PDE3 inhibitor.
Mixture of Ginkgolides A, B and C, found in Gin...
Cathelicidin derivative, antimicrobial peptide,...
D2/3 agonist.
VEGFR inhibitor.
Staurosporine analog; PKC inhibitor, TrkA/B ant...
Antioxidant, vitamin E derivative found in vege...