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Ticagrelor

Product ID T3200
Cas No. 274693-27-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $48.60 In stock
25 mg $81.00 In stock
100 mg $189.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ticagrelor is a clinically approved reversible platelet aggregation inhibitor that exhibits anticoagulant and antithrombotic activities. Ticagrelor is primarily used to increase coronary blood flow velocity and to prevent stroke, heart attack, and myocardial infarction. This compound has a rapid onset and offset of action and has been shown to act as a nucleoside analog with an overall similarity to adenosine; it is an allosteric antagonist for the P2Y12 ADP receptor, inhibiting downstream fibrinogen cross-linking between platelets.

Product Info

Cas No.

274693-27-5

Purity

≥98%

Formula

C23H28F2N6O4S

Formula Wt.

522.57

Chemical Name

(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylthio)- 3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

IUPAC Name

(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3, 4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4, 5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Synonym

AZD-6140

Solubility

DMSO 100 mg/mL (191.36 mM) Ethanol 53 mg/mL (101.42 mM) Water Insoluble

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T3200 MSDS PDF

Info Sheet

T3200 Info Sheet PDF

References

Rahman M, Gustafsson D, Wang Y, et al. Ticagrelor reduces neutrophil recruitment and lung damage in abdominal sepsis. Platelets. 2013 Jul 15. [Epub ahead of print] PMID: 23855479.

Wittfeldt A, Emanuelsson H, Brandrup-Wognsen G, et al. Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans. J Am Coll Cardiol. 2013 Feb 19;61(7):723-7. PMID: 23312702.

Birkeland K, Parra D, Rosenstein R. Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor. J Blood Med. 2010;1:197-219. PMID: 22282698.

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