Norfloxacin Nicotinate

Name: Norfloxacin Nicotinate
SKU: N5769
Availability: InStock

Product ID N5769

Cas No. 118803-81-9

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Norfloxacin is a first generation fluoroquinolone antibiotic that exhibits antibacterial, anti-inflammatory, and anticancer activities. Norfloxacin inhibits DNA gyrase and topoisomerase IV; it is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

Product Info

Cas No.	118803-81-9
Purity	≥98%
Formula	C₁₆H₁₈FN₃O₃ • C₆H₅NO₂
Formula Wt.	442.44
IUPAC Name	1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;pyridine-3-carboxylic acid
Melting Point	220-227°C
Solubility	Soluble in water.
Appearance	White/Slight Yellow Crystal Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	N5769 MSDS PDF
Info Sheet	N5769 Info Sheet PDF

References

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Gómez-Hurtado I, Zapater P, Bellot P, et al. Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis. Hepatology. 2011 Mar;53(3):935-44. PMID: 21374664.

Padeĭskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID: 15002177.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Norfloxacin Nicotinate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Ciclopirox Olamine

Moxifloxacin Hydrochloride

Olsalazine Sodium

CK-636

Valproic Acid Sodium

Lumiracoxib

AZD-3514

Linagliptin

Myclobutanil

N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine

Cetrimide

AEBSF Hydrochloride

Gusacitinib

Olomoucine

SKLB 610

NSC-207895

Fibrinopeptide B, human

Terbinafine Hydrochloride

Darifenacin Hydrobromide

Docosahexaenoic Acid (all cis-4,7,10,13,16,19)

Footer