LKT Labs

Biochemicals for Life Science Research

(R)-Synephrine

(R)-Synephrine

Product ID S9755
Cas No. 614-35-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $46.00 In stock
5 g $65.00 In stock
25 g $215.00 In stock
Bulk Quote

Quicklinks

Description

Synephrine is an endogenous alkaloid that can also be found in citrus fruits, Evodia, and Zanthoxylum. Synephrine exhibits vasoconstrictive, anti-inflammatory, antibacterial, and gastrointestinal motility modulating activities. Synephrine acts as a positive inotrope, activating adrenergic receptors (displaying partial selectivity for α-adrenergic receptors), TAAR-1 receptors, and 5-HT receptors. Synephrine decreases levels of ROS, activity of myeloperoxidase, infiltration of inflammatory cells, and expression of TNF-α and IL-6 in the lungs of animal models of lung injury and inflammation. Additionally, synephrine inhibits gastrointestinal motility and slows gastric emptying.

Product Info

Cas No.

614-35-7
Purity

≥98%
Formula

C9H13NO2
Formula Wt.

167.21
IUPAC Name

[(2R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium
Synonym

R(-)-Synephrine; D-(-)-Synephrine; (-)-Oxedrine
Melting Point

162-164°C
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

S9755 MSDS PDF
Info Sheet

S9755 Info Sheet PDF

References

Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D6958

    Droloxifene Citrate

    Tamoxifen analog; SERM.

    ≥98%
  • V0045

    Valacyclovir Hydrochloride

    Neuraminidase inhibitor.

    ≥98%
  • P200091

    PF-07104091

    CDK2 inhibitor

    ≥98%
  • N7332

    NSI-189

    Stem cell neurogenesis inducer.

    ≥99%
  • A990144

    AZD4320

    Inhibitor of Bcl-2 and Bcl-xL

    ≥99%
  • Q8019

    Quetiapine Fumarate

    5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...

    ≥99%
  • R4132

    RKI-1447

    ROCK1/2 inhibitor.

    ≥98%
  • T5610

    γ-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • V3327

    Virginiamycin Mixture

    Macrolide antibiotic

    ≥97%
  • W7201

    WS6

    Islet α/β cell proliferation stimulator.

    ≥98%
  • E7230

    Ethambutol Dihydrochloride

    Arabinosyl transferase inhibitor.

    ≥98%
  • O9396

    Oxytetracycline

    Tetracycline; protein translation inhibitor.

    ≥96%
  • D3229

    7,8-Dihydrokawain

    Kavalactone originally found in Piper methystic...

    ≥98%
  • D3228

    Dihydromyristicin

    Found in parsley.

    ≥98%
  • O1078

    Octreotide Acetate

    Somatostatin analog, peptide; somatostatin agon...

    ≥95%
  • N8604

    NVP-BGT226

    PI3K and mTOR inhibitor.

    ≥98%
  • C0027

    Cafestol Linoleate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • G1855

    Gentiopicroside

    Secoiridoid glycoside found in Gentiana and Cep...

    ≥95%
  • P9200

    PX-866

    Wortmannin analog; PI3K inhibitor.

    ≥98%
  • D3209

    Diclofenac Sodium

    NSAID; COX-1/2 inhibitor, potential K+ channel ...

    ≥99%